{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T07:00:17Z","timestamp":1791010817379,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":4883,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1991,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The thin afferent nerves were tested quantitatively by determining the thresholds of warmth and pricking pain to argon laser stimulation and by measuring the brain potentials related to pricking pain. In 27 patients with electrophysiologically verified carpal tunnel syndrome these parameters were measured from fingers 3 and 5 on both hands. All patients had had sensory symptoms ranging from 3 months to 25 years. Both the thresholds were elevated (<jats:italic>P<\/jats:italic> &lt;0.05) at finger 3 compared to measurements from finger 5, and compared to finger 3 in a group of 39 controls. Four patients with symptoms for more than 7 years had thresholds below the control values. The power of the pain\u2010evoked brain potentials elicited from finger 3 was lower (<jats:italic>P<\/jats:italic> &lt;0.05) compared to finger 5, and compared to the control group (<jats:italic>P<\/jats:italic> &lt;0.01). No correlations were found between the measured parameters and the clinical electrophysiological investigation. The findings support previous assumptions that chronic low\u2010force compressions cause impairment of intraneural microcirculation, and hence can affect the function of the thin afferents.<\/jats:p>","DOI":"10.1002\/mus.880140604","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T10:32:38Z","timestamp":1104575558000},"page":"508-514","source":"Crossref","is-referenced-by-count":43,"title":["Involvement of thin afferents in carpal tunnel syndrome: Evaluated quantitatively by argon laser stimulation"],"prefix":"10.1002","volume":"14","author":[{"given":"Lars","family":"Arendt\u2010Nielsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Gregersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Egon","family":"Toft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Bjerring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1971.00480340090010"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.42.7.649"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.51.1.35"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198802000-00003"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.5.398"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.5.405"},{"key":"e_1_2_1_8_2","first-page":"397","volume-title":"Pain Measurement in Man","author":"Biehl R","year":"1984"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.37.3.340"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237330"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091450205"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1152\/ajplegacy.1935.114.1.69","article-title":"Afferent function in the group of nerve fibers of slowest conduction velocity","volume":"114","author":"Clark D","year":"1935","journal-title":"Am J Physiol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1989.tb08634.x"},{"key":"e_1_2_1_14_2","first-page":"352","volume-title":"New Developments in Electromyography and Clinical Neurophysiology","author":"Desmedt JE","year":"1973"},{"key":"e_1_2_1_15_2","first-page":"55","volume-title":"Handbook of Electroencephalography and Clinical Neurophysiology","author":"Desmedt JE","year":"1971"},{"key":"e_1_2_1_16_2","first-page":"2","article-title":"Differential tolerance of mammalian myelinated and unmyelinated nerve fibers to oxygen lack","volume":"7","author":"Fink BR","year":"1982","journal-title":"Reg Anesth"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1975.tb00651.x"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(67)90127-6"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.26.5.385"},{"key":"e_1_2_1_20_2","first-page":"35","article-title":"Pain\u2010producing impulses in peripheral nerves","volume":"15","author":"Gasser HS","year":"1935","journal-title":"Proc Ass Res Nerv Ment Dis"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198163030-00009"},{"key":"e_1_2_1_22_2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1152\/ajplegacy.1956.185.1.217","article-title":"Physiology of spinal cord, nerve roots and peripheral nerve compression","volume":"185","author":"Gelfan S","year":"1956","journal-title":"Am J Physiol"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.21.2.109"},{"key":"e_1_2_1_24_2","first-page":"137","article-title":"The effect of treatment on median nerve conduction in patients with the carpal tunnel syndrome","volume":"6","author":"Goodman HV","year":"1961","journal-title":"Ann Phys Med"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1936.004.01.019"},{"key":"e_1_2_1_26_2","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1152\/ajplegacy.1929.89.1.58","article-title":"Effect of anoxemia, carbon dioxide and lactic acid on electrical phenomena of myelinated fibers of the peripheral nervous system","volume":"89","author":"Heinbecker P","year":"1929","journal-title":"Am J Physiol"},{"key":"e_1_2_1_27_2","first-page":"246","article-title":"Effects of ischemia on range of conduction velocities and on facilitation in human motor nerves","volume":"91","author":"Hershey WN","year":"1966","journal-title":"Trans Am Neurol Assoc"},{"key":"e_1_2_1_28_2","first-page":"1219","article-title":"New screening device for assessment of peripheral neuropathy","volume":"28","author":"Katims JJ","year":"1986","journal-title":"J Occupational Med"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/102.3.619"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(82)80175-5"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00687242"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.48.3.250"},{"key":"e_1_2_1_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1975.tb00379.x"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(75)90248-8"},{"key":"e_1_2_1_35_2","first-page":"483","volume-title":"Pathology of Cerebral Microcirculation","author":"Nobel W","year":"1973"},{"key":"e_1_2_1_36_2","first-page":"433","article-title":"Anatomical changes in peripheral nerves compressed by a pneumatic tourniquet","volume":"113","author":"Ochoa J","year":"1972","journal-title":"J Anat"},{"key":"e_1_2_1_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410110207"},{"key":"e_1_2_1_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880080510"},{"key":"e_1_2_1_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(81)80003-2"},{"key":"e_1_2_1_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/66.4.237"},{"key":"e_1_2_1_41_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1041408"},{"key":"e_1_2_1_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091130202"},{"key":"e_1_2_1_43_2","first-page":"711","volume-title":"Nerves and Nerve Injuries","author":"Sunderland S","year":"1978"},{"key":"e_1_2_1_44_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.26.6.520"},{"key":"e_1_2_1_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1989.tb08757.x"},{"key":"e_1_2_1_46_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1942.00200140060005"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.880140604","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.880140604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T23:40:03Z","timestamp":1698018003000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.880140604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,6]]},"references-count":45,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1991,6]]}},"alternative-id":["10.1002\/mus.880140604"],"URL":"https:\/\/doi.org\/10.1002\/mus.880140604","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,6]]}}}