{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:14:52Z","timestamp":1790270092796,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":4730,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1991,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 20\u2010year\u2010old female hospitalized with status asthmaticus was treated with bronchodilators, antibiotics, and high\u2010dose corticosteroids, and was paralyzed with vecuronium for 10 days to facilitate mechanical ventilation. When this was discontinued, she was found to have a flaccid quadriplegia with areflexia and 4\u2010fold elevation in serum creatine kinase. A muscle biopsy showed extensive loss of thick (myosin) myofilaments, sometimes in corelike distribution, with relative preservation of thin (actin) filaments and Z\u2010discs. Muscle strength returned to normal after 2 months. The pathological lesion in this patient's muscle fibers resemble those in rats treated with high doses of corticosteroids following denervation.<\/jats:p>","DOI":"10.1002\/mus.880141115","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T09:47:05Z","timestamp":1104572825000},"page":"1131-1139","source":"Crossref","is-referenced-by-count":195,"title":["Myopathy with thick filament (myosin) loss following prolonged paralysis with vecuronium during steroid treatment"],"prefix":"10.1002","volume":"14","author":[{"given":"Moris J.","family":"Danon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stirling","family":"Carpenter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"1486","article-title":"Myopathie aig\u00fce au d\u00e9cours de \u013e\u00e9tat de mal asthmatique","volume":"19","author":"Bachmann P","year":"1987","journal-title":"Press Med"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","DOI":"10.1097\/00005072-198403000-00010","volume-title":"Pathology of Skeletal Muscle","author":"Carpenter S","year":"1984"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","unstructured":"HaasJL ShaeferMS MiwaLJ: Prolonged paralysis assocaited with long\u2010term pancuronium use.Pharmacotherapy1989;154\u2013157.","DOI":"10.1002\/j.1875-9114.1989.tb04121.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1972.00490150045008"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198708000-00019"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)91471-4"},{"issue":"1","key":"e_1_2_1_8_2","first-page":"207","article-title":"Subacute myopathy with selective loss of thick filaments: A new muscle disease associated with HIV seropositivity","volume":"37","author":"Olney RK","year":"1987","journal-title":"Neurology"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0303-8467(85)90060-5"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880100509"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(86)80719-3"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.29.1.100"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410240114"},{"key":"e_1_2_1_14_2","first-page":"403","article-title":"Muscle weakness and atrophy following prolonged paralysis with Panacuronium bromide in neonates","volume":"18","author":"Torres CF","year":"1985","journal-title":"Ann Neurol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.281.6235.271-a"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1977.00500140068014"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.880141115","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.880141115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T18:58:51Z","timestamp":1695841131000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.880141115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,11]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1991,11]]}},"alternative-id":["10.1002\/mus.880141115"],"URL":"https:\/\/doi.org\/10.1002\/mus.880141115","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,11]]}}}