{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:17:47Z","timestamp":1760782667512},"reference-count":11,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":4700,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1991,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The Lambert\u2010Eaton myasthenic syndrome (LEMS) is an autoimmune disorder of neuromuscular transmission. Electrodiagnosis is confirmed by an increase in compound muscle action potential amplitude during high\u2010frequency repetitive nerve stimulation or following brief exercise. We describe the results of stimulated single\u2010fiber electromyography in 4 patients with disorders of neuromuscular transmission: LEMS (2), LEMS\/myasthenia gravis (MG) overlap (1), and MG (1). Stimulated SFEMG was performed in the extensor digitorum communis muscle with axonal intramuscular suprathreshold stimulation at low and high rates. In all 4 patients, a rate dependence of jitter was found. In LEMS and LEMS\/MG, jitter and blocking improved with high stimulation rates, as compared with the opposite effect in MG. We conclude that stimulated SFEMG is a valuable technique in the diagnosis of LEMS.<\/jats:p>","DOI":"10.1002\/mus.880141215","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T09:49:17Z","timestamp":1104572957000},"page":"1227-1230","source":"Crossref","is-referenced-by-count":19,"title":["Stimulated single\u2010fiber electromyography in lambert\u2010eaton myasthenic syndrome"],"prefix":"10.1002","volume":"14","author":[{"given":"Vinay","family":"Chaudhry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danny F.","family":"Watson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shawn J.","family":"Bird","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David R.","family":"Cornblath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880070311"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880120108"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880120802"},{"key":"e_1_2_1_5_2","first-page":"67","volume-title":"Contemporary Neurology Symposia: The Remote Effects of Cancer on Nervous System","author":"Lambert EH","year":"1965"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/111.3.577"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880090904"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1975.00490540059007"},{"key":"e_1_2_1_9_2","volume-title":"Single Fiber Electromyography","author":"St\u00e5lberg E","year":"1979"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.49.6.677"},{"key":"e_1_2_1_11_2","first-page":"289","article-title":"Tetanic potentiation and depression at single motor end\u2010plates in myasthenia and LEMS","volume":"98","author":"Trontelj JV","year":"1990","journal-title":"J Neurol Sci"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(89)90109-4"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.880141215","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.880141215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T23:05:03Z","timestamp":1698015903000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.880141215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,12]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1991,12]]}},"alternative-id":["10.1002\/mus.880141215"],"URL":"https:\/\/doi.org\/10.1002\/mus.880141215","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,12]]}}}