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However, vasulitic neuropathy may become confluent and present as as distal symmetrical polyneuropathy or occur without systemic necrotizing vasculitis. Distal symmetrical polyneuropathies without associated vasculitis are also common in many connective tissue diseases. Compression neuropathies, especially carpal tunnel syndrome, occur with increased frequency in rheumatoid arthritis. Finally, certain neurpathies may be the major presenting feature of particular connective tissue diseases. For example, trigeminal neuropathy often heralds the onset of systemic sclerosis or mixed connective tissue disease, and sensory neuronopathy may be the initial presenting feature of Sj\u00f6gren's syndrome.<\/jats:p>","DOI":"10.1002\/mus.880150502","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T10:36:11Z","timestamp":1104575771000},"page":"531-542","source":"Crossref","is-referenced-by-count":63,"title":["AAEM minimonograph #38: Neuropathies in connective tissue disease"],"prefix":"10.1002","volume":"15","author":[{"given":"Richard K.","family":"Olney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780310906"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780310907"},{"key":"e_1_2_1_4_2","first-page":"S17","article-title":"The 1987 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