{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T16:29:13Z","timestamp":1789230553569,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":4517,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1992,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We studied neuromuscular transmission in 16 patients with prior poliomyelitis by measuring single fiber electromyographic (SFEMG) jitter. This was compared with 3 indirect methods of assessing reinnervation: SFEMG fiber density, macro EMG, and the presence of fibre type grouping on muscle biopsy. In patients with acute poliomyelitis before the age of 10, there was a positive correlation between the extent of neuromuscular transmission impairment, demonstrated by increased SFEMG jitter, and the enlargement of the motor unit, as indicated by increased fiber density, increased macro EMG signals, and fiber type grouping on muscle biopsy. However, there was no correlation between any of these parameters and the presence or absence of new symptoms of weakness. These findings suggest that impaired neuromuscular transmission is most common in patients with prior poliomyelitis whose motor units have been maximally enlarged by axonal sprouting, but is independent of the presence or absence of new symptoms of weakness.<\/jats:p>","DOI":"10.1002\/mus.880150603","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T10:36:51Z","timestamp":1104575811000},"page":"648-655","source":"Crossref","is-referenced-by-count":32,"title":["Neuromuscular transmission as a function of motor unit size in patients with prior polimyelitis"],"prefix":"10.1002","volume":"15","author":[{"given":"Ricardo A.","family":"Maselli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil R.","family":"Cashman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Wollman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar F.","family":"Salazar\u2010Grueso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Roos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1977.sp011716"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(79)90241-5"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1973.sp010319"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1974.sp010670"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198707023170102"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198604103141505"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880130214"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.3109\/02844317409084397"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/287649a0"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1523\/JNEUROSCI.05-07-01896.1985","article-title":"Effects of changes in motor unit size on transmitter release at the frog neuromuscular junction","volume":"5","author":"Herrera AA","year":"1985","journal-title":"J Neurosci"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1523\/JNEUROSCI.10-05-01522.1990","article-title":"Age differences in morphology of reinnervation of partially denervated mouse muscle","volume":"10","author":"Jacob JM","year":"1990","journal-title":"J Neurosci"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1989.00520410036019"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)91154-X"},{"key":"e_1_2_1_15_2","first-page":"31","article-title":"A case of progressive muscular atropy occurring in men who has had acute poliomyelitis nineteen years previouly","volume":"16","author":"Potts CS","year":"1903","journal-title":"Univ Penn Med Bull"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880130802"},{"key":"e_1_2_1_17_2","first-page":"225","article-title":"Paralysie essentielle de \u013eenfance: atrophie musculaire cons\u00e9cutive","volume":"4","author":"Raymond M","year":"1875","journal-title":"Gaz Med (Paris)"},{"key":"e_1_2_1_18_2","series-title":"Birth Defects Original Article Series","first-page":"189","volume-title":"Research and Clinical Aspects of the Late Effects of Poliomyelitis","author":"Sanders DB","year":"1987"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(75)90166-5"},{"key":"e_1_2_1_20_2","volume-title":"Single Fiber Electromyography","author":"Stalberg E","year":"1979"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880060902"},{"key":"e_1_2_1_22_2","unstructured":"StalbergE:Capability of motor unit sprouting in neuromuscular disorders AAEE Didactic Program 34th Annual Meeting 1987."},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880040610"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880110412"}],"container-title":["Muscle &amp; 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