{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:11:21Z","timestamp":1791263481940,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":4517,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1992,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The latency fluctuation of single motor unit potentials (MUP<jats:sub>H<\/jats:sub>) in the H\u2010reflex is greater than the latency fluctuation of MUPs in the direct (MUP<jats:sub>M<\/jats:sub>) and recurrent (MUP<jats:sub>F<\/jats:sub>) responses. This has been attributed to the variability in the impulse generation at the site of nerve stimulation, and to the variation in the synaptic delay at the anterior horn cell. We studied the latency fluctuation of single motor unit H\u2010reflex in patients with motor neuron disorders (MND) in comparison with normal subjects. The mean jitter of the H\u2010reflex was 264.3 \u00b1 17.8 \u03bcs (mean \u00b1 SEM) in 30 MUP<jats:sub>H<\/jats:sub> recorded from 10 patients with ALS, 302.7 \u00b1 25.2 \u03bcs in 16 MUP<jats:sub>H<\/jats:sub> from 6 patients with chronic motor neuron diseases, as compared with 137.4 \u00b1 7.3 \u00b5s in 34 MUP<jats:sub>H<\/jats:sub> recorded from 10 normal subjects. This difference, which persisted even after the correction for the latency variation of MUP<jats:sub>M<\/jats:sub>, cannot be explained on the basis of an enhanced reciprocal inhibition. Thus, the increased latency fluctuation of the single motor unit H\u2010reflex in patients with MND may reflect changes in the motoneuron pool excitability that may be secondary to altered intrinsic electrophysiological properties of motoneurons, or to an abnormal temporal and spatial summation of synaptic inputs on motoneurons.<\/jats:p>","DOI":"10.1002\/mus.880150604","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T10:36:51Z","timestamp":1104575811000},"page":"656-660","source":"Crossref","is-referenced-by-count":12,"title":["Single motor unit H\u2010reflex in motor neuron disorders"],"prefix":"10.1002","volume":"15","author":[{"given":"Betty","family":"Soliven","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo A.","family":"Maselli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"884","article-title":"Increased reciprocal I\u2010A inhibition following spinal cord injury in human","volume":"16","author":"Boorman G","year":"1990","journal-title":"Soc Neurosci (Abstr)"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1984.52.3.435"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1987.sp016652"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1957.sp005778"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1965.sp007552"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880120702"},{"key":"e_1_2_1_8_2","first-page":"874a","article-title":"The evaluation of central monosynaptic transmission using single motor unit studies","volume":"13","author":"Jabre JF","year":"1990","journal-title":"Muscle Nerve"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1985.sp015892"},{"key":"e_1_2_1_10_2","first-page":"219","article-title":"Electrophysiological studies of reflex activity in patients with lesions of the nervous system. 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II","volume":"91","author":"Teasdall RD","year":"1952","journal-title":"Bull John Hopkins Hosp"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/2201043a0"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.36.6.951"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.880150604","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.880150604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T20:53:03Z","timestamp":1698094383000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.880150604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,6]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1992,6]]}},"alternative-id":["10.1002\/mus.880150604"],"URL":"https:\/\/doi.org\/10.1002\/mus.880150604","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,6]]}}}