{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:18:14Z","timestamp":1762100294841},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":3361,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1995,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We tested for HTLV\u2010I proviral DNA in skeletal muscle from patients with polymyositis infected with HTLV\u2010I using the in situ polymerase chain reaction. We found the HTLV\u2010I provirus in some of the CD4\u2010positive cells in HTLV\u2010I\u2010positive polymyositis cases but not in HTLV\u2010I\u2010negative polymyositis ones. We could not detect HTLV\u2010I within the muscle fibers. We suggest that HTLV\u2010I\u2010associated polymyositis is not due to direct, persistent infection of the muscle fiber by the virus, but to a T\u2010cell\u2010mediated immunological process triggered by the HTLV\u2010I\u2010infected cells. \u00a9 1995 John Wiley &amp; Sons, Inc.<\/jats:p>","DOI":"10.1002\/mus.880180809","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T02:38:28Z","timestamp":1104547108000},"page":"854-858","source":"Crossref","is-referenced-by-count":28,"title":["Detection of HTLV\u2010I provirus by in situ polymerase chain reaction in mononuclear inflammatory cells in skeletal muscle of viral carriers with polymyositis"],"prefix":"10.1002","volume":"18","author":[{"given":"I.","family":"Higuchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Kashio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Izumo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Inose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Izumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Ohkubo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Arimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Osame","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410160206"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199111213252107"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/362359a0"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(86)80180-0"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.19.6207"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880160507"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880150108"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.23.7588"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.31.973"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(92)90012-A"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410230111"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.14.5620"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1993.1451"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410360414"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880160411"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00571876"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/310505a0"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)91793-5"},{"key":"e_1_2_1_20_2","first-page":"1239","article-title":"An improved technique for the in situ detection of DNA after polymerase chain reaction amplification","volume":"139","author":"Nuovo GJ","year":"1991","journal-title":"Am J Pathol"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198904133201507"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/299367a0"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-419X(87)90003-5"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910330606"}],"container-title":["Muscle &amp; 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