{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T04:30:49Z","timestamp":1764304249954,"version":"3.32.0"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,2,22]],"date-time":"2006-02-22T00:00:00Z","timestamp":1140566400000},"content-version":"vor","delay-in-days":52,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Science Council of the Republic of China","award":["NSC 92-2320-B-040-036","NSC 93-2320-B-040-065","NSC 94-2320-B-040-026"],"award-info":[{"award-number":["NSC 92-2320-B-040-036","NSC 93-2320-B-040-065","NSC 94-2320-B-040-026"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To clarify the contributions of parasympathetic inputs and outputs to the micturition reflex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Intra\u2010vesical pressure (IVP), external urethral sphincter electromyogram (EMG), pelvic afferent nerve activities (PANA), and pelvic efferent nerve activities (PENA) as well as the time\u2010derived IVP (dIVP, an index of bladder contractility) were evaluated in intact and acute dorsal or ventral root(s) rhizotomized (DRX and VRX, respectively) rats.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In DRX rats, when compared with that in intact stage, the voiding frequency was decreased (75\u2009\u00b1\u200915% of intact,<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05, n\u2009=\u20098), while the threshold pressure to trigger voiding contractions was significantly increased (187\u2009\u00b1\u200975% of intact,<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05, n\u2009=\u20098). In addition, several insufficient contractions (5.3\u2009\u00b1\u20093.5 contractions\/voiding,<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05, n\u2009=\u20098) occurred in ahead of each voiding contraction. On the other hand, in VRX rats, the peak and rebound IVP were significantly decreased (90\u2009\u00b1\u20093.5% and 75\u2009\u00b1\u200911.3% of intact,<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01, n\u2009=\u20098), while the threshold pressure was not affected (102\u2009\u00b1\u200911% of intact,<jats:italic>P<\/jats:italic>\u2009=\u2009NS, n\u2009=\u20098). The time\u2010derived parameters were significantly decreased in VRX (peak dIVP, 78\u2009\u00b1\u200910.2%, rebound dIVP, 75\u2009\u00b1\u200915.6%, minimal dIVP, 68\u2009\u00b1\u200914% of intact,<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01, n\u2009=\u20098) but only peak dIVP was decreased (85\u2009\u00b1\u200911% of intact,<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01, n\u2009=\u20098) in DRX rats.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Acute selective DRX and VRX rat can be an animal model to investigate peripheral neural control in micturition functions. Neurourol. Urodynam. 25:283\u2013289, 2006. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.20220","type":"journal-article","created":{"date-parts":[[2006,2,22]],"date-time":"2006-02-22T23:16:32Z","timestamp":1140650192000},"page":"283-289","source":"Crossref","is-referenced-by-count":4,"title":["Impaired micturition reflex caused by acute selective dorsal or ventral root(s) rhizotomy in anesthetized rats"],"prefix":"10.1002","volume":"25","author":[{"given":"Jiuan\u2010Miaw","family":"Liao","sequence":"first","affiliation":[{"name":"Department of Physiology, College of Medicine Chung\u2010Shan Medical University Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen\u2010Li","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Urology Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin\u2010Da","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Physical Therapy, College of Medicine Chung\u2010Shan Medical University Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gin\u2010Den","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital Chung\u2010Shan Medical University Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo\u2010Jung","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Physiology, College of Medicine Chung\u2010Shan Medical University Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao\u2010Hsun","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cosmetic Science Providence University Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shwu\u2010Fen","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Biotechnology Ming\u2010Chuan University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei\u2010Jung","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Applied Cosmetic Ching\u2010Kuo Institute of Management and Health Keelong Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei\u2010Chen","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Medicine Kao\u2010Hsiung Medical University Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzer\u2010Bin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Physiology, College of Medicine Chung\u2010Shan Medical University Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,22]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1970.sp009240"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1990.tb12956.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(99)00508-4"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00187.2002"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(75)90417-5"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.41.1.691"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1992.9.123"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/S0022-3565(24)29617-8","article-title":"Central muscarinic mechanisms regulating voiding in rats","volume":"297","author":"Ishiura Y","year":"2001","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2001.280.5.R1407"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"R1157","DOI":"10.1152\/ajpregu.1993.264.6.R1157","article-title":"Changes in bladder and external urethral sphincter function after spinal cord injury in the rat","volume":"264","author":"Kruse MN","year":"1993","journal-title":"Am J Physiol\u2010Regulatory Integrative Comp Physiol"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(98)00298-5"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(91)91495-M"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1523\/JNEUROSCI.21-02-00559.2001","article-title":"Coordination of bladder detrusor and external urethral sphincter in a rat model of spinal cord injury: Effect of injury severity","volume":"21","author":"Pikov V","year":"2001","journal-title":"J Neurosci"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.300.2.421"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)49164-6"},{"key":"e_1_2_1_17_1","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0094-0143(21)00507-3","article-title":"Urologic complications of spinal cord injury","volume":"20","author":"Selzman AA","year":"1993","journal-title":"Urol Clin Am"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1992.68.5.1473"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20211"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.20220","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.20220","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.20220","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T21:13:47Z","timestamp":1736284427000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.20220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["10.1002\/nau.20220"],"URL":"https:\/\/doi.org\/10.1002\/nau.20220","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"type":"print","value":"0733-2467"},{"type":"electronic","value":"1520-6777"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}