{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:11:09Z","timestamp":1772118669028,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,10,31]],"date-time":"2006-10-31T00:00:00Z","timestamp":1162252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Potassium sensitivity test (PST) has been used as an optional tool in diagnosing painful bladder syndrome\/interstitial cystitis (PBS\/IC). The role of PST in the follow\u2010up of patients with PBS\/IC is elusive. We performed PST before and after treatment of PBS\/IC with cyclosporine A (CyA) or pentosan polysulfate sodium (PPS), to test whether the result of repeated PST correlates with alleviation of PBS\/IC\u2010related symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Sixty\u2010four patients who participated in a randomized clinical study comparing CyA and PPS in the treatment of PBS\/IC were recruited to the present study. Patients underwent 0.4 M PST before and after 6 months of treatment. The primary end point was a change from positive PST to negative among patients who responded to both treatments determined by global response assessment (GRA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Potassium sensitivity test (PST) was more likely to change from positive to negative among patients who responded to their treatment according to GRA (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). The PST change follows the clinical course (ICSI score, voiding frequency, VAS score), which was more beneficial in the CyA\u2010treated patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Potassium sensitivity test (PST) reflects symptom severity of PBS\/IC patients. Change of pre\u2010treatment positive PST to negative correlates well with clinical alleviation of PBS\/IC\u2010related symptoms. In patients with persistent symptoms it may be painful and does not offer additional information. Thus, we do not recommend PST to be used as a routine clinical test in monitoring of PBS\/IC treatment efficacy. Neurourol. Urodynam. 26:267\u2013270, 2007. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.20350","type":"journal-article","created":{"date-parts":[[2006,10,31]],"date-time":"2006-10-31T16:58:30Z","timestamp":1162313910000},"page":"267-270","source":"Crossref","is-referenced-by-count":20,"title":["Potassium sensitivity test (PST) as a measurement of treatment efficacy of painful bladder syndrome\/interstitial cystitis: A prospective study with cyclosporine A and pentosan polysulfate sodium"],"prefix":"10.1002","volume":"26","author":[{"given":"Jukka","family":"Sairanen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teuvo L. J.","family":"Tammela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikael","family":"Leppilahti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markku","family":"Onali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tapio","family":"Forsell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirja","family":"Ruutu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,31]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199909010-00018"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)66981-9"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000081163.46167.82"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)41529-1"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64678-2"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-005-1306-5"},{"key":"e_1_2_1_8_1","first-page":"309","article-title":"Urodynamic results of intravesical heparin therapy for women with frequency urgency syndrome and interstitial cystitis","volume":"100","author":"Kuo HC","year":"2001","journal-title":"J Formos Med Assoc"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0162-3109(00)00192-2"},{"key":"e_1_2_1_10_1","first-page":"171","article-title":"Potassium sensitivity test","volume":"2","author":"Parsons CL","year":"1996","journal-title":"Technol Urol"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00180-5"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.1930130503"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(01)01586-2"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64909-9"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000181808.45786.84"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(01)01131-1"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.20350","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.20350","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T22:58:54Z","timestamp":1700521134000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.20350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,31]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1002\/nau.20350"],"URL":"https:\/\/doi.org\/10.1002\/nau.20350","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1064720.517634","asserted-by":"object"}]},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,31]]}}}