{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T18:12:40Z","timestamp":1776017560065,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T00:00:00Z","timestamp":1172793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Life-Tech, Inc."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To investigate bladder diary measurements from asymptomatic subjects in separate night and day periods, including their relationships to age and total volume voided. A major objective of this study was to generate age\u2010adjusted reference values against which clinical measurements of nocturia can be compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Three\u2010day bladder diaries were collected from 161 females and 92 males (age: median\u2009=\u200946.5 years; range\u2009=\u200919.6\u201384.6 years). We studied: average volume voided (\u201cV<jats:sub>avg<\/jats:sub>\u201d), voiding frequency, and four urine production measures (volume, production rate, and their ratios to 24\u2010hr values)<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both day and night V<jats:sub>avg<\/jats:sub> and frequency increase with increasing volume. The night increase is much steeper than the day increase. With aging, frequency increases, V<jats:sub>avg<\/jats:sub> decreases, day production decreases and night production increases. These age effects are steeper for males than females. Adjusting for age by regression analysis reduces the night production measure's variability by about 40%, and expressing production rate as a percent of the 24\u2010hr value reduces the variability by an additional 20%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We present regression equations that can be used to adjust night and day V<jats:sub>avg<\/jats:sub> frequency and production rate reference values for the influences of age and total volume. Using these equations, we calculated a table of 95% confidence limits of night urine production and night frequency. The least variable night urine volume measurement studied was night\/24\u2010hr production rate; hence this may prove to be the most efficacious measurement to use in detecting nocturnal polyuria. Neurourol. Urodynam. 26:465\u2013473, 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.20355","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T01:34:39Z","timestamp":1172885679000},"page":"465-473","source":"Crossref","is-referenced-by-count":45,"title":["Normative bladder diary measurements: Night versus day"],"prefix":"10.1002","volume":"26","author":[{"given":"Matthew","family":"Parsons","sequence":"first","affiliation":[{"name":"Birmingham Women's Hospital  Birmingham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Tissot","sequence":"additional","affiliation":[{"name":"William Beaumont Hospital  Royal Oak, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Cardozo","sequence":"additional","affiliation":[{"name":"King's College Hospital  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ananias","family":"Diokno","sequence":"additional","affiliation":[{"name":"Department of Urology William Beaumont Hospital  Royal Oak, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cindy L.","family":"Amundsen","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Division of Urogynecology Duke University Medical Center  Durham, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred C.","family":"Coats","sequence":"additional","affiliation":[{"name":"Life\u2010Tech, Inc.  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