{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T07:04:51Z","timestamp":1783407891213,"version":"3.54.6"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,2,5]],"date-time":"2007-02-05T00:00:00Z","timestamp":1170633600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Danish Research Foundation"},{"name":"Sahva Foundation"},{"name":"Fabrikant Mads Clausen Foundation"},{"DOI":"10.13039\/100008361","name":"Danish Multiple Sclerosis Society","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008361","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Transcutaneous electrical stimulation of the dorsal penile\/clitoral nerve (DPN) has been shown to suppress detrusor contractions in patients with neurogenic detrusor overactivity (NDO). However, the long\u2010term use of surface electrodes in the genital region may not be well tolerated and may introduce hygienic challenges. The aim of this study was to assess whether electrical stimulation of the sacral dermatomes could suppress detrusor contractions in multiple sclerosis (MS) patients with NDO, hereby providing an alternative to DPN stimulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A total of 14 MS patients (8 M, 6 F) with low bladder capacity (&lt;300 ml) and a recent urodynamic study showing detrusor overactivity incontinence participated in the study. Three successive slow fill cystometries (16 ml\/min) were carried out in each patient. The first filling served as control filling where no stimulation was applied. In the second and third filling electrical stimulation of either the DPN or sacral dermatomes was applied automatically whenever the detrusor pressure exceeded 10 cmH<jats:sub>2<\/jats:sub>O.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The control filling showed detrusor overactivity in 12 of the 14 patients. In 10 of the 12 patients one or more detrusor contractions could be suppressed with DPN stimulation. Electrical stimulation of the sacral dermatomes failed to suppress detrusor contractions in all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although therapeutic effects may be present from stimulation of the sacral dermatomes, we were unable to demonstrate any acute effects during urodynamics. For this reason stimulation of the sacral dermatomes is not an option in a system that relies on the acute suppression of a detrusor contraction. Neurourol. Urodynam. 26:525\u2013530, 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.20363","type":"journal-article","created":{"date-parts":[[2007,2,5]],"date-time":"2007-02-05T22:17:36Z","timestamp":1170713856000},"page":"525-530","source":"Crossref","is-referenced-by-count":25,"title":["Electrical stimulation of sacral dermatomes in multiple sclerosis patients with neurogenic detrusor overactivity"],"prefix":"10.1002","volume":"26","author":[{"given":"M.V.","family":"Fjorback","sequence":"first","affiliation":[{"name":"Center for Sensory\u2010Motor Interaction (SMI), Department of Health Science and Technology Aalborg University  Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.S.","family":"Van Rey","sequence":"additional","affiliation":[{"name":"Radboud University Nijmegen Medical Centre  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.J.M.","family":"Rijkhoff","sequence":"additional","affiliation":[{"name":"Center for Sensory\u2010Motor Interaction (SMI), Department of Health Science and Technology Aalborg University  Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"N\u00f8hr","sequence":"additional","affiliation":[{"name":"Department of Urology Aalborg Hospital  Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Petersen","sequence":"additional","affiliation":[{"name":"The Centre for Multiple Sclerosis in Ry  Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.P.","family":"Heesakkers","sequence":"additional","affiliation":[{"name":"Radboud University Nijmegen Medical Centre  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,6,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)02243-4"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000080377.71804.fd"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)01070-0"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00007835"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1403.2003.03024.x"},{"key":"e_1_2_1_7_1","unstructured":"FjorbackMV RijkhoffNJM Sinkj\u00e6rT et al.2004.\u201cConditional Electrical Stimulation of the Dorsal Penile\/Clitoral Nerve for Management of Neurogenic Detrusor Overactivity in Multiple Sclerosis\u201d International continence society 34th annual meeting August 24th\u201327th 2004 Paris France."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(98)90003-X"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20131"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2004.01.001"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000158160.11083.1b"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)66075-0"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101177"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2005.29044.x"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2002.28817"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2004.09.004"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)61760-9"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)51928-X"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000162035.73977.1c"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-4096.2001.02422.x"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20118"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00256804"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/1520-6777(2001)20:1<73::AID-NAU9>3.0.CO;2-3"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1191\/0269215504cr803oa"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.20363","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.20363","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.20363","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T15:29:56Z","timestamp":1696951796000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.20363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6,18]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1002\/nau.20363"],"URL":"https:\/\/doi.org\/10.1002\/nau.20363","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6,18]]}}}