{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T15:31:40Z","timestamp":1784734300800,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,3,19]],"date-time":"2009-03-19T00:00:00Z","timestamp":1237420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Obstructive symptoms such as slow stream, dribbling and straining are often reported by painful bladder syndrome and interstitial cystitis (PBS\/IC) patients. Our hypothesis was that some patients with PBS\/IC have an associated measurable bladder outlet obstruction (BOO) secondary to dysfunctional voiding and that those patients with more severe PBS\/IC are more likely to have BOO.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective chart review of female patients diagnosed with PBS\/IC based on the NIDDK research definition. Charts were reviewed for clinical symptom severity, ulcer or non\u2010ulcer PBS\/IC on cystoscopy, and pressure\u2010flow urodynamics (UDPF). Patients were excluded if they had a urinary infection at the time of urodynamics or did not meet study entry requirements. The cut\u2010off values of \u226412 ml\/sec and \u226525 cm of water was used to define BOO.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 231 women: 38 had ulcer PBS\/IC and 193 had non\u2010ulcer PBS\/IC. MCC was 269 ml in non\u2010ulcer PBS\/IC and 200 ml in ulcer PBS\/IC (<jats:italic>P<\/jats:italic>\u2009=\u20090.006). One hundred eleven women (48%) met criteria for obstruction. MCC was 298 ml in the non\u2010obstructed group and 214 ml in the obstructed group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). The maximum flow with non\u2010ulcer PBS\/IC was 11.0 ml\/sec and in ulcer PBS\/IC 8.9 ml\/sec (<jats:italic>P<\/jats:italic>\u2009=\u20090.04) Detrusor pressure at maximum flow was 33.3 cm H<jats:sub>2<\/jats:sub>O, in non\u2010ulcer, and 37.4 cm H<jats:sub>2<\/jats:sub>O in ulcer PBS\/IC (<jats:italic>P<\/jats:italic>\u2009=\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Forty\u2010eight percent of our PBS\/IC patients have BOO, and increasing severity of PBS\/IC is associated with higher voiding pressure. Neurourol. Urodynam. 28:944\u2013948, 2009. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.20729","type":"journal-article","created":{"date-parts":[[2009,3,19]],"date-time":"2009-03-19T16:09:20Z","timestamp":1237478960000},"page":"944-948","source":"Crossref","is-referenced-by-count":36,"title":["Bladder outlet obstruction in painful bladder syndrome\/interstitial cystitis"],"prefix":"10.1002","volume":"28","author":[{"given":"Anne P.","family":"Cameron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy B.","family":"Gajewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,3,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)02243-4"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.11.084"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.03.086"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00634-1"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1520-6777(2000)19:5<553::AID-NAU2>3.0.CO;2-B"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.04.089"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67552-0"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000075272"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)68947-1"},{"key":"e_1_2_1_11_2","first-page":"59","article-title":"Proposed urodynamic pressure\u2010flow nomograms to diagnose female bladder outlet obstruction","volume":"76","author":"Di GE","year":"2004","journal-title":"Arch Ital Urol Androl"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)61948-7"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-2042.10.s1.6.x"},{"key":"e_1_2_1_14_2","first-page":"4","article-title":"The diagnosis of interstitial cystitis","volume":"29","author":"Messing EM","year":"1987","journal-title":"Urology"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(75)90012-6"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.02.067"},{"key":"e_1_2_1_17_2","first-page":"S3","article-title":"Bladder outlet obstruction: Etiology and evaluation","volume":"7","author":"Dmochowski RR","year":"2005","journal-title":"Rev Urol"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-0143(05)70319-0"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)59235-6"},{"key":"e_1_2_1_20_2","first-page":"154","article-title":"Pelvic floor behavior and interstitial cystitis","volume":"9","author":"Schmidt RA","year":"1991","journal-title":"Semin Urol"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2007.07191.x"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.05.157"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.07.031"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncpuro0378"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2005.05.047"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)69849-5"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2006.06335.x"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2008.02134.x"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.20729","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.20729","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T23:25:16Z","timestamp":1700522716000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.20729"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3,19]]},"references-count":27,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["10.1002\/nau.20729"],"URL":"https:\/\/doi.org\/10.1002\/nau.20729","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3,19]]}}}