{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T18:15:41Z","timestamp":1784139341512,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2001,12,6]],"date-time":"2001-12-06T00:00:00Z","timestamp":1007596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Lundbergs Foundation"},{"DOI":"10.13039\/100010107","name":"Anna-Lisa and Bror Bj\u00f6rnssons Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100010107","id-type":"DOI","asserted-by":"crossref"}]},{"name":"M\u00e4rtha and Gustaf \u00c5grens Research Foundation"},{"name":"Medical Faculty-Gothenburg"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Overactive bladder dysfunction is an expression of defective neuromuscular control of the lower urinary tract. The causes and the way to classify this problem are currently under debate. In some patients the overactive bladder is one sign of a neurological disorder, in so called \u201cidiopathic detrusor instability\u201d the cause is less obvious. That an overactive bladder has a neurogenic cause is a reasonable hypothesis. We made a detailed neurological investigation in 45 patients with idiopathic overactive bladder. Cerebrospinal fluid (CSF) was examined and blood tests for vitamin B<jats:sub>12<\/jats:sub>and folic acid deficiency were checked, too. In 37 of the 45 patients (82%) pathological signs were observed in the neurological tests. The most common finding was central or peripheral paresis of the legs appearing in 24 patients (53%). Of the 45 patients, eight received a neurological diagnosis, definite or possible MS or dorsal column sensation neuropathy. The results of this study give an indication of the importance of the neurological examination and suggest that neuropathy might not be uncommon in patients with so\u2010called idiopathic detrusor instability. This also invites to reconsideration of the current classification. It is possible that a new classification based on a functional view could provide a better fundament in the search of etiologic and pathogenetic factors and also guide in the selection of the treatment most optimal for the individual patient. Neurourol. Urodynam. 21:65\u201370, 2002. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/nau.2094","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T22:16:03Z","timestamp":1030313763000},"page":"65-70","source":"Crossref","is-referenced-by-count":21,"title":["Neurological signs are common in patients with urodynamically verified \u201cidiopathic\u201d bladder overactivity"],"prefix":"10.1002","volume":"21","author":[{"given":"Jarl","family":"Ahlberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christer","family":"Edlund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Wikkels\u00f6","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Rosengren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Fall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001,12,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2000.tb16925.x"},{"key":"e_1_2_1_3_1","first-page":"5","article-title":"The standardisation of terminology of lower urinary tract function. 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A physiologic approach to the treatment of urinary incontinence","volume":"18","author":"Fall M","year":"1991","journal-title":"Urol Clin North Am"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.1930140605"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.55.11.986"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)68062-7"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6777(1998)17:2<89::AID-NAU2>3.0.CO;2-8"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(97)00187-3"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004150070130"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1990.tb03507.x"},{"key":"e_1_2_1_20_1","unstructured":"Kobelt\u2010NguyenG JohannessonM MattiassonA.1997.Correlations between symptoms of urge incontinence and scores of generic quality of life instruments (SF 36) and health status measurements (EuroQoL) and between changes in symptoms and QoL scores (abstract). 27th Annual Meeting of the International Continence Society Yokohama Japan: 23\u20137."},{"key":"e_1_2_1_21_1","first-page":"1772","article-title":"Urininkontinens \u2014 en kostnadskr\u00e4vande folksjukdom","volume":"89","author":"Milsom I","year":"1992","journal-title":"L\u00e4kartidningen"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1985.tb07023.x"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)66614-X"},{"issue":"9","key":"e_1_2_1_24_1","first-page":"2068","article-title":"Senile dementia of the Binswanger's type","volume":"58","author":"Olsen CG","year":"1998","journal-title":"Am Fam Physician"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(96)00079-2"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)68558-8"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.1994.tb00060.x"},{"issue":"1","key":"e_1_2_1_28_1","first-page":"228","article-title":"Therapeutic effects of dopamine D1\/D2 receptor agonists on detrusor hyperreflexia in 1\u2010methyl\u20104\u2010phenyl\u20101,2,3,6\u2010tetrahydropyridine\u2010lesioned parkinsonian cynomolgus monkeys","volume":"286","author":"Yoshimura N","year":"1998","journal-title":"J Pharmacol Exp Ther"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.2094","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.2094","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T01:09:18Z","timestamp":1700528958000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.2094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12,6]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,1]]}},"alternative-id":["10.1002\/nau.2094"],"URL":"https:\/\/doi.org\/10.1002\/nau.2094","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12,6]]}}}