{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:15:21Z","timestamp":1791090921212,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,1,20]],"date-time":"2011-01-20T00:00:00Z","timestamp":1295481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Pfizer, Inc."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The purpose of this study was to assess the validity of the Urinary Sensation Scale (USS) in men with overactive bladder and voiding symptoms (OAB\u2010LUTS) and women with overactive bladder (OAB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from two OAB clinical trials of tolterodine were used. The USS, a 5\u2010point scale, assesses the amount of urinary urgency associated with each urination. Three methods to calculate the USS are: mean urgency (Mean USS); mode urgency (Mode USS); and sum urgency (sum USS). The validity and responsiveness of the scoring methods was assessed using Spearman's correlations, general linear models, and effect sizes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data from 650 men (Study 1) and 413 women (Study 2) were analyzed. Mean age was 65.2 (men) and 47.8 (women); 70% were Caucasian in both studies. Correlations of USS scores with bladder diary variables were small to moderate and higher among Sum USS than Mean USS (r\u2009=\u20090.02\u20130.64). Correlations among the USS and patient\u2010reported outcomes (PROs) were again small to moderate and higher with Sum USS (r\u2009=\u20090.05\u20130.41). Both the Mean USS and Sum USS significantly discriminated (all <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) among all bladder diary variables (except nocturia and UUI in men) when grouped as improved\/not improved as well as by the PROs. Effect sizes for men and women, respectively, were \u22120.52 and \u22121.09 for Mean USS and \u22120.72 and \u22121.36 for Sum USS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The USS is a valid and highly responsive measure of urinary urgency in men with OAB\u2010LUTS and women with OAB. Neurourol. Urodynam. 30:360\u2013365, 2011. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.21005","type":"journal-article","created":{"date-parts":[[2011,1,20]],"date-time":"2011-01-20T20:27:33Z","timestamp":1295555253000},"page":"360-365","source":"Crossref","is-referenced-by-count":42,"title":["Validation of the urinary sensation scale (USS)"],"prefix":"10.1002","volume":"30","author":[{"given":"Karin S.","family":"Coyne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Kay","family":"Margolis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ray","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasudha","family":"Vats","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher R.","family":"Chapple","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,1,20]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.09.019"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2001.02228.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)02243-4"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20915"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)02505-0"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000170235.22776.1a"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000165461.38088.7b"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2005.05345.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-008-0770-0"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.04.047"},{"key":"e_1_2_5_12_2","unstructured":"EMEA Committee for Proprietary Medicinal Products.Note for guidance on the clinical investigation of medicinal productsfor the treatment of urinary incontinence. 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