{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T01:41:15Z","timestamp":1780623675047,"version":"3.54.1"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,3]],"date-time":"2015-12-03T00:00:00Z","timestamp":1449100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to identify the clinical features of patients with obstructive sleep apnea syndrome (OSAS) and investigate the impact of continuous positive airway pressure (CPAP) treatment on nocturnal urine volume.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This study enrolled 53 patients with moderate\u2010to\u2010severe OSAS and an apnea\u2010hypoxia index of &gt;20\/hr. Data were collected on serum brain natriuretic peptide (BNP) level, International Prostate Symptom Score\u2010Quality of Life (IPSS\u2010QOL) score, Overactive Bladder Symptom Score (OABSS), International Consultation on Incontinence Modular Questionnaire\u2010Nocturia QOL (ICIQ\u2010NQOL) score, Epworth Sleepiness Scale (ESS) score, and the frequency volume chart. Only patients who continued CPAP treatment for 3 months were included in the analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 40 patients (33 men and 7 women) completed the study (75.5%). The mean age was 56.9 years. The night\u2010time frequency to void was significantly decreased from 2.1 to 1.2 after CPAP treatment (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). The mean scores as assessed by ESS, IPSS\u2010QOL, OABSS, and ICIQ\u2010NQOL significantly improved after CPAP (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). The mean diastolic blood pressure significantly decreased after CPAP treatment. However, there was no significant change in the BNP level before and after CPAP treatment. In the frequency volume chart, hours of undisturbed sleep, total nocturnal voided volume, and nocturnal polyuria index significantly improved after CPAP treatment (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). However, 24\u2010hr voided volume and mean voided volume during night\u2010time did not change after CPAP treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CPAP treatment decreases night\u2010time urinary frequency by reducing nocturnal urine production and improves QOL in patients with OSAS. <jats:italic>Neurourol. 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