{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:12:35Z","timestamp":1762506755634},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,2,16]],"date-time":"2016-02-16T00:00:00Z","timestamp":1455580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine the ability of Peristeen<jats:bold>\u00ae<\/jats:bold> transanal irrigation system to reduce symptoms of neurogenic bowel dysfunction (NBD) in patients using the validated neurogenic bowel dysfunction scoring system for the pediatric population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients 3\u201321 years with NBD whose current bowel program was unsuccessful were given the Neurogenic Bowel Dysfunction (NBoDS) score sheet before initiating Peristeen\u00ae, and at 2 weeks, 2 months, and 6 months after. All patients were started on Peristeen<jats:bold>\u00ae<\/jats:bold> with tap water (20\u2009ml\/kg) per daily irrigation. Mean and paired <jats:italic>t<\/jats:italic>\u2010tests were completed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>24 patients were enrolled and had follow\u2010up. Mean age was 10.5 years (range 3\u201321 years), 25%, 50%, 25% had thoracic, lumbar and sacral level lesions respectively. Mean NBoDS score at initiation of Peristeen\u00ae was 20.21 (\u00b15.56), n\u2009=\u200924. The mean score after two weeks of use was 12.75 (\u00b14.40), n\u2009=\u200924. There was a statistically significant decrease of 7.46 (95%CI, 5.07\u20139.84) points, t(23)\u2009=\u20096.47, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0005 after two weeks. There was a statistically significant decrease in their scores from initiation to the 2 month time period of 7.00 (95%CI, 2.18\u201311.82) points, t(9)\u2009=\u20093.29, <jats:italic>P<\/jats:italic>\u2009=\u20090.009. By the sixth month of daily use the mean NBoDS score was 9.67 (n\u2009=\u200912). This was an average decrease of 8.83 (95%CI, 5.39\u201312.28) points from initiation score, t(11)\u2009=\u20095.641, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.005.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The Peristeen\u00ae transanal irrigation system provides a significant reduction in NBoDS scores in pediatric patients with NBD. Peristeen\u00ae should be considered when other conservative bowel management options have been unsuccessful. <jats:italic>Neurourol. Urodynam. 36:632\u2013635, 2017<\/jats:italic>. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.22979","type":"journal-article","created":{"date-parts":[[2016,2,16]],"date-time":"2016-02-16T10:08:42Z","timestamp":1455617322000},"page":"632-635","source":"Crossref","is-referenced-by-count":17,"title":["Prospective evaluation of Peristeen<b>\u00ae<\/b> transanal irrigation system with the validated neurogenic bowel dysfunction score sheet in the pediatric population"],"prefix":"10.1002","volume":"36","author":[{"given":"Maryellen S.","family":"Kelly","sequence":"first","affiliation":[{"name":"Department of Urology Duke University Medical Center Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crystal","family":"Dorgalli","sequence":"additional","affiliation":[{"name":"Children's Hospital of Orange County Pediatric Urology Center Orange California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon","family":"McLorie","sequence":"additional","affiliation":[{"name":"Children's Hospital of Orange County Pediatric Urology Center Orange California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine E.","family":"Khoury","sequence":"additional","affiliation":[{"name":"Children's Hospital of Orange County Pediatric Urology Center Orange California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,16]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"9","article-title":"Spina bifida and anencephaly prevalence\u2014United States, 1991\u20132001","volume":"51","author":"Matthews TJ","year":"2002","journal-title":"MMWR Recomm Rep"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2084"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/ptj\/82.6.601","article-title":"Neurogenic bladder, neurogenic bowel and sexual dysfunction in people with spinal cord injury","volume":"82","author":"Benevento BT","year":"2002","journal-title":"Phys Ther"},{"key":"e_1_2_6_5_1","first-page":"661","article-title":"Management of neurogenic bowel dysfunction","volume":"47","author":"Paris G","year":"2011","journal-title":"Eur J Phys Rehabil Med"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-0277"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2223\/JPED.2199"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2013.8"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-0277"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmr.2014.09.007"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101705"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00152192-200411000-00005"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22248"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22694"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2012.146"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/cch.12117"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.06.004"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2008.98"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/954315"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.11.036"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13101"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.1263"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.22979","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.22979","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.22979","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T18:09:30Z","timestamp":1696356570000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.22979"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,16]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1002\/nau.22979"],"URL":"https:\/\/doi.org\/10.1002\/nau.22979","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,16]]}}}