{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T02:29:29Z","timestamp":1789439369044,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T00:00:00Z","timestamp":1470268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>AIMS<\/jats:title><jats:p>The purpose of this study was to evaluate lower urinary tract symptoms (LUTS) in idiopathic normal pressure hydrocephalus (iNPH).<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Patients with new\u2010onset iNPH were prospectively evaluated for LUTS via detailed history and physical, and administration of questionnaires from the International Consultation on Incontinence to assess incontinence (ICIq\u2010UI), overactive bladder (ICIq\u2010OAB), and quality of life (ICIq\u2010LUTqol), as well as the American Urological Association Symptom Score bother scale. All patients with moderate\u2010to\u2010severe LUTS were offered urodynamic testing. Sub\u2010analysis was performed based on gender, medical comorbidities, and age.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Fifty\u2010five consecutive patients with iNPH completed the initial evaluation and surveys. Total urinary incontinence score was mild to moderate (8.71\u2009\u00b1\u20090.64: 0\u201321 scale) with 90.9% experiencing leakage and 74.5% reporting urge incontinence. The most common OAB symptom was nocturia (2.2\u2009\u00b1\u20090.14: 0\u20134 scale) with urge incontinence the most bothersome (3.71\u2009\u00b1\u20090.44: 0\u201310 scale). Quality\u2010of\u2010life impact was moderate (4.47\u2009\u00b1\u20090.4: 0\u201310 scale) and American Urological Association Symptom Score bother scale was 2.89\u2009\u00b1\u20090.22 (0\u20136 scale). Urodynamics testing revealed 100% detrusor overactivity and mean bladder capacity of 200\u2009mL. Several differences were identified based on gender, medical comorbidities, and age.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Patients with iNPH present with mild\u2010moderate incontinence of which nocturia is the most common symptom, urge incontinence the most bothersome, with 100% of patients having detrusor overactivity. Younger patients experienced greater bother related to LUTS. To our knowledge, this is the only prospective evaluation of urinary symptoms in patients with new\u2010onset iNPH.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23084","type":"journal-article","created":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T13:14:12Z","timestamp":1470316452000},"page":"1167-1173","source":"Crossref","is-referenced-by-count":23,"title":["Characterization of lower urinary tract symptoms in patients with idiopathic normal pressure hydrocephalus"],"prefix":"10.1002","volume":"36","author":[{"given":"Sarah C.","family":"Krzastek","sequence":"first","affiliation":[{"name":"Division of Urology Department of Surgery Virginia Commonwealth University School of Medicine Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William M.","family":"Bruch","sequence":"additional","affiliation":[{"name":"Division of Urology Department of Surgery Virginia Commonwealth University School of Medicine Richmond 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