{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:51:18Z","timestamp":1783464678728,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,11,4]],"date-time":"2016-11-04T00:00:00Z","timestamp":1478217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","award":["2012\u201011004"],"award-info":[{"award-number":["2012\u201011004"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To investigate which urodynamic parameters are associated with renal deterioration over a median of 41 years follow\u2010up after traumatic spinal cord injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records of patients with a traumatic spinal cord injury sustained 1944\u20101975 were reviewed from time of injury until 2012. Patients who attended regular renography and\/or renal clearance examinations and had minimum one cystometry and pressure\u2010flow study were included. Renal deterioration was diagnosed as split renal function \u226430% in one kidney or relative glomerular filtration rate \u226451% of expected according to age and gender. Detrusor function, presence of detrusor sphincter dyssynergia, maximum detrusor pressure, post\u2010void residual volume, and cystometric bladder capacity were obtained. In patients with detrusor overactivity, a detrusor overactivity\/cystometry ratio was calculated using duration of detrusor contraction(s) during filling cystometry divided by total duration of filling cystometry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 73 patients were included in the study, and the median follow\u2010up time was 41 years after injury (range 24\u201056). Sixty\u2010four patients (88%) used reflex triggering or bladder expression as bladder emptying method for the longest period after injury. During follow\u2010up 60% changed to clean intermittent catheterization. The majority of the patients (68%) had neurogenic detrusor overactivity. In 35 patients, a detrusor\u2010overactivity\/cystometry ratio could be calculated and a detrusor overactivity\/cystometry ratio\u2009&gt;\u20090.33 was significantly associated with renal deterioration (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.02). No significant association was found between maximum detrusor pressure or other urodynamic parameters and renal deterioration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Duration of detrusor overactivity longer than one third of the duration of cystometry is associated with renal deterioration after spinal cord injury.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23163","type":"journal-article","created":{"date-parts":[[2016,11,4]],"date-time":"2016-11-04T07:31:06Z","timestamp":1478244666000},"page":"1607-1615","source":"Crossref","is-referenced-by-count":29,"title":["Renal deterioration after spinal cord injury is associated with length of detrusor contractions during cystometry\u2014A study with a median of 41 years follow\u2010up"],"prefix":"10.1002","volume":"36","author":[{"given":"Marlene","family":"Elmelund","sequence":"first","affiliation":[{"name":"Clinic for Spinal Cord Injuries, Rigshospitalet University of Copenhagen Hornb\u00e6k Denmark"},{"name":"Department of Obstetrics and Gynecology, Herlev Hospital University of Copenhagen Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"Klarskov","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Herlev Hospital University of Copenhagen Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Bagi","sequence":"additional","affiliation":[{"name":"Department of Urology, Rigshospitalet University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter S.","family":"Oturai","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fin","family":"Biering\u2010S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Clinic for Spinal Cord Injuries, Rigshospitalet University of Copenhagen Hornb\u00e6k Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3100638"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.07457.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2015.242"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.04.028"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)54449-3"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22984"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)37254-3"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)41319-X"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/10790268.1998.11719505"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.5535\/arm.2014.38.3.353"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/01952307.1993.11735878"},{"key":"e_1_2_7_13_1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0094-0143(21)00996-4","article-title":"Hydroureteronephrosis after spinal cord injury. 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