{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T20:11:34Z","timestamp":1773173494357,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,4,13]],"date-time":"2017-04-13T00:00:00Z","timestamp":1492041600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:sec><jats:title>AIMS<\/jats:title><jats:p>Vaginal reconstructive surgery can be performed with or without mesh. We sought to determine comparative rates of perioperative complications of native tissue versus vaginal mesh repairs for pelvic organ prolapse.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Using the National Surgical Quality Improvement Program (NSQIP) database, we concatenated surgical data from vaginal procedures for prolapse repair, including anterior and posterior colporrhaphy, paravaginal defect repair, enterocele repair, and vaginal colpopexy using Current Procedural Terminology (CPT) coding. We stratified this data by the modifier associated with mesh usage at the time of the procedure. We then compared 30\u2010day perioperative outcomes, postoperative complications (bleeding, infection, etc), and readmission rates between women with and without mesh\u2010based repairs.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>We identified 10\u2009657 vaginal reconstructive procedures without mesh and 959 mesh\u2010based repairs from 2009 through 2013. Patients undergoing mesh repair were more likely to experience at least one complication than native tissue repair (9.28% vs 6.15%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), with the overall complication rate also being higher in the mesh group (11.37% vs 9.39%, <jats:italic>P<\/jats:italic>\u2009=\u20090.03). Procedures with mesh had a higher rate of perioperative bleeding requiring transfusion than native tissue repair (2.3% vs 0.49%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), and organ surgical site infection (SSI) (0.52% vs 0.17%, <jats:italic>P<\/jats:italic>\u2009=\u20090.02). There were no significant differences in rates of readmission, superficial, or deep SSIs, pneumonia, urinary tract infection, sepsis, or renal failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The use of vaginal mesh for pelvic organ prolapse repair appears to result in a higher rate of perioperative complications than native tissue repair. Patients undergoing these procedures should be counselled preoperatively concerning these risks.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23231","type":"journal-article","created":{"date-parts":[[2017,4,13]],"date-time":"2017-04-13T18:37:03Z","timestamp":1492108623000},"page":"2044-2048","source":"Crossref","is-referenced-by-count":17,"title":["Short\u2010term complications associated with the use of transvaginal mesh in pelvic floor reconstructive surgery: Results from a multi\u2010institutional prospectively maintained dataset"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5352-5968","authenticated-orcid":false,"given":"Maxx","family":"Caveney","sequence":"first","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devin","family":"Haddad","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Matthews","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"},{"name":"Department of Urology Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gopal","family":"Badlani","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"},{"name":"Department of Urology Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majid","family":"Mirzazadeh","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"},{"name":"Department of Urology Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.08.022"},{"key":"e_1_2_7_3_1","article-title":"Serious complications associated with transvaginal placement of surgical mesh in repair of pelvic organ prolapse and stress urinary incontinence","author":"Schultz D","year":"2008","journal-title":"Public Health Notifications"},{"key":"e_1_2_7_4_1","unstructured":"US Food and Drug Administration a. Urogynecologic Surgical Mesh: update on the Safety and Effectiveness of Transvaginal Placement for Pelvic Organ Prolapse.2011. Available at:http:\/\/www.fda.gov\/downloads\/MedicalDevices\/Safety\/AlertsandNotices\/UCM262760.pdf"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001451"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2007.02.024"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-1830-z"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012079"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009521"},{"key":"e_1_2_7_10_1","unstructured":"American College of Surgeons National Surgical Quality Improvement Program: history. [Website].2016. Available at:https:\/\/www.facs.org\/quality\u2010programs\/acs\u2010nsqip\/program\u2010specifics\/history. Accessed April 01 2016 2016."},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2012.11.013"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.09.031"},{"key":"e_1_2_7_13_1","unstructured":"ACS NSQIP: data Collection analysis and reporting.2016. Available at:https:\/\/www.facs.org\/quality\u2010programs\/acs\u2010nsqip\/program\u2010specifics\/data. Accessed 06\/11\/2016."},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.5173\/ceju.2014.03.art17"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-0879-9"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13224-013-0396-0"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-015-3724-z"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22396"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12454"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-012-2383-6"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22740"},{"key":"e_1_2_7_22_1","first-page":"Cd04014","article-title":"Surgical management of pelvic organ prolapse in women","author":"Maher C","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.2.510"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.23231","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.23231","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T02:55:51Z","timestamp":1696042551000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.23231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,13]]},"references-count":22,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1002\/nau.23231"],"URL":"https:\/\/doi.org\/10.1002\/nau.23231","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,13]]}}}