{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T10:37:32Z","timestamp":1777113452092,"version":"3.51.4"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T00:00:00Z","timestamp":1490918400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aims to identify the predictors for detrusor overactivity (DO) in women following extensive vaginal pelvic reconstructive surgery (PRS) for advanced pelvic organ prolapse (POP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 1503 women who had prolapse POP\u2010Q stage\u2009\u2265\u20093 and underwent vaginal PRS with or without MUS from January 2006 to December 2015. All subjects completed a 72\u2010h voiding diary, IIQ\u20107, UDI\u20106, POPDI\u20106, and PISQ\u201012. Urodynamics (UDS) was performed pre\u2010 and post\u2010operatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 1503 women, 56 patients were excluded due to incomplete data. Women who had trans\u2010vaginal mesh were 1083 of 1447 (74.8%) and concomitant MUS were 353 (24.4%). Pre\u2010operative DO were 245 (16.9%) and 24.5% (60\/245) of them continued to have persistent DO post\u2010operatively. Women who had normal pre\u2010operative stable detrusor were 1202 (83.1%) and 3.5% (30\/1202) developed de novo DO post\u2010operatively. The overall incidence of post\u2010operative DO was 6.2% (90\/1447). Patients with age \u226566 year, neurological factors like Cerebrovascular accident and Parkinsonian disease, pre\u2010operative bladder outlet obstruction (BOO) maximum urethral closure pressure (MUCP) \u226560\u2009cmH<jats:sub>2<\/jats:sub>O, Maximum flow rate (MFR) &lt;15\u2009mL\/s and detrusor at maximum flow (Dmax) \u226520\u2009cmH<jats:sub>2<\/jats:sub>O) and post\u2010void residue (PVR) \u2265200\u2009mL hold a significant higher risk of developing DO either persistent or de novo following PRS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Age \u226566 year, neurological factors like CVA and Parkinsonian disease, pre\u2010operative MUCP \u226560\u2009cmH<jats:sub>2<\/jats:sub>O, MFR\u2009&lt;\u200915\u2009mL, Dmax\u2009\u2265\u200920\u2009cmH<jats:sub>2<\/jats:sub>O, and PVR\u2009\u2265\u2009200\u2009mL are independent risk factors for developing post\u2010operative DO following vaginal PRS for advanced POP.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23273","type":"journal-article","created":{"date-parts":[[2017,4,3]],"date-time":"2017-04-03T20:37:09Z","timestamp":1491251829000},"page":"192-199","source":"Crossref","is-referenced-by-count":23,"title":["Predictors for detrusor overactivity following extensive vaginal pelvic reconstructive surgery"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3885-1359","authenticated-orcid":false,"given":"Tsia\u2010Shu","family":"Lo","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital Keelung Medical Center Keelung, Taiwan People's Republic of China"},{"name":"Division of Urogynecology, Department of Obstetrics and Gynecology, Linkou, Chang Gung Memorial Hospital Linkou Medical Center Taoyuan, Taiwan People's Republic of China"},{"name":"Department of Obstetrics and Gynaecology, Chang Gung Memorial Hospital Xiamen Medical Center Xiamen People's Republic of China"},{"name":"Chang Gung University School of Medicine Taoyuan, Taiwan People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shailaja","family":"Nagashu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Peoples Education Society Medical College and Research Centre Kuppam, Andhra Pradesh India"},{"name":"Fellow, Division of Urogynaecology, Department of Obstetrics and Gynaecology, Chang Gung Memorial Hospital Linkou Medical Center Taoyuan, Taiwan People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu\u2010Chiao","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Division of Urogynecology, Department of Obstetrics and Gynecology, Linkou, Chang Gung Memorial Hospital Linkou Medical Center Taoyuan, Taiwan People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma Clarissa","family":"Uy\u2010Patrimonio","sequence":"additional","affiliation":[{"name":"Fellow, Division of Urogynaecology, Department of Obstetrics and Gynaecology, Chang Gung Memorial Hospital Linkou Medical Center Taoyuan, Taiwan People's Republic of China"},{"name":"Department of Obstetrics and Gynecology Dr. Pablo O. Torre Memorial Hospital Bacolod City Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Yi\u2010Hao","sequence":"additional","affiliation":[{"name":"Division of Urogynecology, Department of Obstetrics and Gynecology, Linkou, Chang Gung Memorial Hospital Linkou Medical Center Taoyuan, Taiwan People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-0976-9"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0b013e32833e498a"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.17772\/gp\/557"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-013-2200-1"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2014.02.013"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-014-2492-9"},{"key":"e_1_2_8_8_1","first-page":"286","article-title":"Miya Hook ligature carrier for sacrospinous ligament suspension","volume":"70","author":"Miyazaki FS","year":"1987","journal-title":"Obstet Gynecol"},{"key":"e_1_2_8_9_1","first-page":"S66","article-title":"Prevalence of overactive bladder in women: results from the NOBLE program","volume":"12","author":"Stewart WF","year":"2001","journal-title":"Int Urogynaecol J"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2001.02228.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2003.11.003"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.03.010"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00587-6"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20487"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20858"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)41846-5"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-4096.2003.05059.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-2000-z"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.06.064"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00634-1"},{"key":"e_1_2_8_21_1","first-page":"S32","article-title":"Evaluation of voiding dysfunction and measurement of bladder volume","volume":"6","author":"Christopher E","year":"2004","journal-title":"Rev Urol"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31817615b2"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.02915.x"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-006-0004-2"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2007.057232"},{"key":"e_1_2_8_26_1","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1097\/GCO.0b013e32834a926e","article-title":"Predictors for overactive bladder symptoms after pelvic organ prolapse surgery","volume":"23","author":"de Boer TA","year":"2011","journal-title":"Curr Opin Obstet Gynecol"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.23273","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.23273","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/nau.23273","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.23273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T07:15:44Z","timestamp":1694243744000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.23273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,31]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1002\/nau.23273"],"URL":"https:\/\/doi.org\/10.1002\/nau.23273","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,31]]}}}