{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:40:25Z","timestamp":1791988825224,"version":"4.4.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T00:00:00Z","timestamp":1492732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>Single\u2010incision vaginal mesh (SIVM) procedures for pelvic organ prolapse (POP) differed in mesh fabrication and implantation that may affect treatment outcomes. We aim to evaluate and compare the safety and effectiveness of two SIVM procedures, and explore factors that may have associations with surgical effectiveness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Our data of using two SIVM procedures for a total (anterior and posterior) vaginal mesh repair were studied. Patients who had \u2267stage 2 POP and underwent either Elevate (<jats:italic>n<\/jats:italic>\u2009=\u200985) using anchored, lightweight meshes or Prosima procedures (<jats:italic>n<\/jats:italic>\u2009=\u200995) using non\u2010anchored, original meshes were assessed. A detailed comparison of 1 year outcomes was made.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 180 patients, 172 (95.6%) attended the 1\u2010year follow\u2010up. Demographic data were similar between groups except a higher average age (64.5 vs 60.4, <jats:italic>P<\/jats:italic>\u2009=\u20090.001) was noted in the Elevate (<jats:italic>n<\/jats:italic>\u2009=\u200984) group compared to the Prosima (<jats:italic>n<\/jats:italic>\u2009=\u200988) group. Surgical results were also similar except a significantly higher objective cure (POP stage \u22661) rate (89.3% vs 78.4%, <jats:italic>P<\/jats:italic>\u2009=\u20090.042) was noted in the Elevate group. The safety profile favored Elevate with a lower, but not statistically significant, rate (4.7% vs 12.5%, <jats:italic>P<\/jats:italic>\u2009=\u20090.106) of vaginal mesh exposure. After a statistical analysis, we found anatomic recurrence (POP stage \u22672) after the SIVM procedures had strong (<jats:italic>P\u2009<\/jats:italic>&lt;\u20090.05) associations with \u201cearly surgical cases,\u201d \u201cProsima procedure,\u201d \u201cadvanced cystocele (Ba\u2009&gt;\u2009+3\u2009cm),\u201d and \u201cprior prolapse repair,\u201d respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Beyond a learning curve, Elevate performed better than Prosima in POP repair regarding surgical effectiveness. Meanwhile, several predisposing factors that may affect recurrence after SIVM procedures were found.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23292","type":"journal-article","created":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T19:52:44Z","timestamp":1492804364000},"page":"298-306","source":"Crossref","is-referenced-by-count":8,"title":["Factors that affect outcomes of prolapse repair using single\u2010incision vaginal mesh procedures"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8791-3253","authenticated-orcid":false,"given":"Hsiao\u2010Yun","family":"Hsieh","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching\u2010Pei","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih\u2010Ku","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pao\u2010Sheng","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Statistics Tunghai University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao\u2010Ching","family":"Hung","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology China Medical University School of Medicine Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man\u2010Jung","family":"Hung","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology China Medical University School of Medicine Taichung Taiwan"},{"name":"Department of Obstetrics and Gynecology Asia University Hospital Taichung Taiwan"},{"name":"Department of Biotechnology Asia University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-007-0457-y"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.01.051"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-013-2200-1"},{"key":"e_1_2_7_5_1","first-page":"CD004014","article-title":"Surgical management of pelvic organ prolapse in women","volume":"4","author":"Maher C","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_6_1","unstructured":"U.S. Food and Drug Administration FDA News Release (January 4 2016): FDA strengthens requirements for surgical mesh for the transvaginal repair of pelvic organ prolapse to address safety risks. 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