{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T20:49:25Z","timestamp":1768078165168,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T00:00:00Z","timestamp":1497830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01DK083538"],"award-info":[{"award-number":["R01DK083538"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["K12 HD43489"],"award-info":[{"award-number":["K12 HD43489"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To describe a sensory map of pelvic dermatomes in women with Interstitial Cystitis\/Bladder Pain Syndrome (IC\/BPS). We hypothesized that if IC\/BPS involves changes in central processing, then women with IC\/BPS will exhibit sensory abnormalities in neurologic pelvic dermatomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Women with IC\/BPS and healthy controls underwent neurologic examination that included evaluation of sharp pain sensitivity and vibration in dermatomes T12, L1, L2, S1\u20105. Peripheral nervous system sensitivity to pressure, vibration, and pinprick were scored using numeric rating scales (NRS). Bilateral comparisons were made with Wilcoxon signed\u2010rank test and comparisons between groups were made by the Mann\u2010Whitney <jats:italic>U<\/jats:italic>\u2010test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Total of 74 women with IC\/BPS and 36 healthy counterparts were included. IC\/BPS and control groups had similar age (43.0\u2009\u00b1\u200914.1 and 38.6\u2009\u00b1\u200915.3 years, <jats:italic>P<\/jats:italic>\u2009=\u20090.14) and BMI (28.9\u2009\u00b1\u20098.0\u2009kg\/m<jats:sup>2<\/jats:sup> and 26.9\u2009\u00b1\u20098.4\u2009kg\/m<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic>\u2009=\u20090.24), respectively. Women with IC\/BPS reported hyperalgesia (elevated bilateral NRS pain intensity) in all pelvic dermatomes compared to healthy controls. S4\u2010S5 region had the highest pain intensity in all participants. All IC\/BPS participants exhibited vibration sensation hypoesthesia, at least unilaterally, in all of the pelvic dermatomes except L1 compared to healthy controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This detailed map of neurologic pelvic dermatomes in women with IC\/BPS found hyperalgesia in all pelvic dermatomes, and some evidence of vibration sensation hypoesthesia, compared to healthy controls. These findings support the hypothesis that IC\/BPS may involve changes in central signal processing biased towards nociception.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23330","type":"journal-article","created":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T12:56:43Z","timestamp":1497877003000},"page":"458-465","source":"Crossref","is-referenced-by-count":8,"title":["Sensory mapping of pelvic dermatomes in women with interstitial cystitis\/bladder pain syndrome"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7044-9917","authenticated-orcid":false,"given":"Tatiana","family":"Sanses","sequence":"first","affiliation":[{"name":"University of Maryland School of Medicine Baltimore Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"McCabe","sequence":"additional","affiliation":[{"name":"Case Western Reserve University Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Zhong","sequence":"additional","affiliation":[{"name":"Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aisha","family":"Taylor","sequence":"additional","affiliation":[{"name":"University Hospitals Cleveland Medical Center Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisela","family":"Chelimsky","sequence":"additional","affiliation":[{"name":"Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sangeeta","family":"Mahajan","sequence":"additional","affiliation":[{"name":"University Hospitals Cleveland Medical Center Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Buffington","sequence":"additional","affiliation":[{"name":"The Ohio State University Columbus Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adonis","family":"Hijaz","sequence":"additional","affiliation":[{"name":"University Hospitals Cleveland Medical Center Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Ialacci","sequence":"additional","affiliation":[{"name":"Case Western Reserve University Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Janata","sequence":"additional","affiliation":[{"name":"University Hospitals Cleveland Medical Center Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Chelimsky","sequence":"additional","affiliation":[{"name":"Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.01.086"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2174\/157339711102150702112236"},{"key":"e_1_2_7_4_1","volume-title":"A Workshop on Chronic Overlapping Pain Conditions","author":"NINDS","year":"2012"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.08.024"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2006.12.025"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.01.025"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000158452.15915.e2"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20178"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20676"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.11.099"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S58853"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.09.019"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0000000000000307"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e3181a68c64"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000106939.41855.36"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.05.023"},{"key":"e_1_2_7_18_1","first-page":"185","article-title":"Factors influencing vibration sense thresholds used to assess occupational exposures to hand transmitted vibration","volume":"48","author":"Harada N","year":"1991","journal-title":"Br J Ind Med"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.12.2245"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2003.10.016"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)42297-X"},{"key":"e_1_2_7_22_1","first-page":"S36","article-title":"Neuromodulation for the treatment of refractory interstitial cystitis","volume":"4","author":"Peters KM","year":"2002","journal-title":"Rev Urol"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2010.05.002"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.150.3699.971"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.01.012"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cognition.2016.06.002"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.23330","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.23330","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/nau.23330","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.23330","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T07:18:03Z","timestamp":1694243883000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.23330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,19]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1002\/nau.23330"],"URL":"https:\/\/doi.org\/10.1002\/nau.23330","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,19]]}}}