{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T02:26:33Z","timestamp":1790043993931,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T00:00:00Z","timestamp":1520294400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To assess whether the urodynamic parameters of mean voided volume, peak detrusor overactivity (DO) pressure, bladder compliance, capacity, and volume at first detrusor overactivity during filling cystometry can predict a successful outcome at first stage tined lead placement (FSTLP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ninty\u2010nine consecutive patients with urodynamically proven idiopathic detrusor overactivity (IDO) refractory to medical treatment and opting for Sacral Nerve Stimulation (SNS), were assessed pre and post FSTLP. Data from 3\u2010day frequency\u2010volume charts, and patient reported (subjective) outcomes were used to assess success or failure after FSTLP. Success was defined as improvement in symptoms &gt;50%. Binary logistic regression analysis was used to ascertain whether key parameters at filling cystometrogram were predictors for success prior to FSTLP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Binary logistic regression analysis did not demonstrate any significant relationship between the five parameters at urodynamics and outcome at FSTLP (<jats:italic>B\u2009<\/jats:italic>&lt;\u20090.01, <jats:italic>P<\/jats:italic>\u2009&gt;\u20090.16) for all parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results from this prospective analysis on patients with IDO refractive to medical therapy referred for SNS would suggest that aside from proving DO at urodynamics as a pre\u2010requisite for intervention as per NICE and EAU guidelines, no parameter is predictive for a successful outcome at FSTLP.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23383","type":"journal-article","created":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T09:03:00Z","timestamp":1520326980000},"page":"1007-1010","source":"Crossref","is-referenced-by-count":18,"title":["Predicting a successful outcome in sacral neuromodulation testing: Are urodynamic parameters prognostic?"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6099-9344","authenticated-orcid":false,"given":"Richard P.","family":"Nobrega","sequence":"first","affiliation":[{"name":"Speciality Registrar in Urological Surgery Oxford Deanery\/Clinical Research Fellow in Urodynamics at University College Hospital at Westmoreland Street Marylebone London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eskinder","family":"Solomon","sequence":"additional","affiliation":[{"name":"Principal Clinical Scientist University College Hospital at Westmoreland Street Marylebone London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Jenks","sequence":"additional","affiliation":[{"name":"Clinical Nurse Specialist University College Hospital at Westmoreland Street Marylebone London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamsin","family":"Greenwell","sequence":"additional","affiliation":[{"name":"Consultant Urological Surgeon University College Hospital at Westmoreland Street Marylebone London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Ockrim","sequence":"additional","affiliation":[{"name":"Consultant Urological Surgeon University College Hospital at Westmoreland Street Marylebone London"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1985.tb07023.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1995.tb07777.x"},{"key":"e_1_2_5_4_1","unstructured":"https:\/\/www.nice.org.uk\/Guidance\/CG97(accessed Nov 16)"},{"key":"e_1_2_5_5_1","unstructured":"https:\/\/www.nice.org.uk\/guidance\/cg171(accessed Nov 16)"},{"key":"e_1_2_5_6_1","first-page":"300","article-title":"Urinary bladder and sphincter responses to stimulation of dorsal and ventral sacral roots","volume":"16","author":"Schmidt RA","year":"1979","journal-title":"Invest Urol"},{"key":"e_1_2_5_7_1","unstructured":"http:\/\/www.accessdata.fda.gov\/cdrh_docs\/pdf\/P970004S004b.pdf(accessed Nov 16)"},{"key":"e_1_2_5_8_1","unstructured":"MedtronicINC Communications Nov 2016"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)00326-5"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20786"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22544"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.06.142"},{"key":"e_1_2_5_13_1","unstructured":"BrazzelliM MurrayA FraserC GrantA. 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