{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T05:34:19Z","timestamp":1783056859162,"version":"3.54.6"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,3,11]],"date-time":"2018-03-11T00:00:00Z","timestamp":1520726400000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>We conducted a nationwide survey on perioperative management and antimicrobial prophylaxis of transvaginal mesh surgeries for pelvic organ prolapse in Japan to understand the practice and risk factors for surgical site infection (SSI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Health records of women undergoing tension\u2010free vaginal mesh (TVM) surgeries from 2010 to 2012 were obtained from 135 medical centers belonging to the Japanese Society of Pelvic Organ Prolapse Surgery. The questionnaire addressed hospital volume, perioperative management, and SSI. Risk factors for SSI were investigated by comparing cases with and without SSI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The hospital volume among institutions varied from 0 to 248 per year (median 16.7). Preoperative hair removal, bowel preparation, and urine culture were routinely performed at 74 (55%), 66 (49%), and 24 (18%) hospitals, respectively. Prophylactic antimicrobials used were mostly first\u2010generation (43%) or second\u2010generation (42%) cephalosporin. SSI was reported in 86 of 9323 patients (0.92%). A multivariate analysis indicated lower hospital volume (odds ratio [OR], 0.995 [by 1\u2010point increase]; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), preoperative bowel preparation (OR, 2.08; <jats:italic>P<\/jats:italic>\u2009=\u20090.013), non\u2010routine urine culture (OR, 3.00; <jats:italic>P<\/jats:italic>\u2009=\u20090.0006), and the use of antibiotics other than first\u2010generation cephalosporin (OR, 5.29; <jats:italic>P<\/jats:italic>\u2009=\u20090.0011) as significant risk factors for SSI. In contrast, the cut\u2010off points of hospital volume for preventing SSI was 116.7 cases (area under curve: 0.61).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of SSI in TVM surgeries was 0.92% in Japan. Lower hospital volume, bowel preparation, non\u2010routine preoperative urine culture, and prophylactic antibiotics other than first\u2010generation cephalosporin significantly elevated the incidence of SSI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23416","type":"journal-article","created":{"date-parts":[[2018,3,12]],"date-time":"2018-03-12T03:12:38Z","timestamp":1520824358000},"page":"1074-1081","source":"Crossref","is-referenced-by-count":4,"title":["Risk factors for surgical site infection after transvaginal mesh placement in a nationwide Japanese cohort"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0069-7392","authenticated-orcid":false,"given":"Jun","family":"Kamei","sequence":"first","affiliation":[{"name":"Department of Urology The University of Tokyo Graduate School of Medicine Tokyo Japan"},{"name":"The Japanese Research Group for Urinary Tract Infection (JRGU) Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Yazawa","sequence":"additional","affiliation":[{"name":"The Japanese Research Group for Urinary Tract Infection (JRGU) Japan"},{"name":"Yazawa Clinic Saitama Japan"},{"name":"Department of Urology School of Medicine Keio University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"The Japanese Research Group for Urinary Tract Infection (JRGU) Japan"},{"name":"Department of Urology Hyogo College of Medicine Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoto","family":"Kaburaki","sequence":"additional","affiliation":[{"name":"The Japanese Research Group for Urinary Tract Infection (JRGU) Japan"},{"name":"Department of Urology School of Medicine Keio University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Urology Nihon University School of Medicine Tokyo Japan"},{"name":"The Japanese Society of Pelvic Organ Prolapse Surgery (JPOPS) Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masami","family":"Takeyama","sequence":"additional","affiliation":[{"name":"Urogynecology Center First Towakai Hospital Osaka Japan"},{"name":"The Japanese Society of Pelvic Organ Prolapse Surgery (JPOPS) Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayasu","family":"Koyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Osaka City University Graduate School of Medicine Osaka Japan"},{"name":"The Japanese Society of Pelvic Organ Prolapse Surgery (JPOPS) Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukio","family":"Homma","sequence":"additional","affiliation":[{"name":"Department of Urology The University of Tokyo Graduate School of Medicine Tokyo Japan"},{"name":"Department of Urology Japan Red Cross Medical Center Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soichi","family":"Arakawa","sequence":"additional","affiliation":[{"name":"The Japanese Research Group for Urinary Tract Infection (JRGU) Japan"},{"name":"Department of Urology Sanda City Hospital Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kiyota","sequence":"additional","affiliation":[{"name":"The Japanese Research Group for Urinary Tract Infection (JRGU) Japan"},{"name":"Department of Urology Jikei University School of Medicine Katsushika Medical Center Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-1088-2"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/luts.12111"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00058-6"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/MOU.0000000000000177","article-title":"What part does mesh play in urogenital prolapse management today","volume":"25","author":"Costantini E","year":"2015","journal-title":"Curr Opin Urol"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-016-3256-5"},{"key":"e_1_2_8_7_1","unstructured":"Communication FS. 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