{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:53:15Z","timestamp":1786978395434,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T00:00:00Z","timestamp":1523318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To investigate storage symptoms following robot\u2010assisted laparoscopic radical prostatectomy (RARP), focused on de novo overactive bladder (OAB), and to evaluate the factors related to de novo OAB occurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We prospectively examined 245 patients without OAB who underwent RARP for localized prostate\u2009cancer. Subjective and objective symptoms in the lower urinary tract were evaluated before and after surgery. At 3 months after RARP, the patients were divided into two groups: patients with de novo OAB (de novo OAB group) and those without OAB (OAB\u2010free group). We compared the operative and urodynamic parameters between both groups and evaluated the factors related to OAB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>De novo OAB was observed in 37.8% (87\/230) of patients. Post\u2010operative continence rate was significantly higher in the OAB\u2010free group (79.7%) than in the de novo OAB group (8.0%). Although the International Prostate Symptom Score (IPSS) and Overactive Bladder Symptom Score (OABSS) in the de novo OAB group significantly deteriorated from 9.7 to 14.1 and from 2.4 to 8.3, respectively, no corresponding significant changes occurred in the OAB\u2010free group. Additionally, there was a significant difference in pre\u2010operative IPSS\u2010QOL score, continence rate, pre\u2010and post\u2010operative maximum urethral closing pressure (MUCP), and post\u2010operative functional profile length (FPL) between both groups. Multivariable logistic regression analysis showed pre\u2010operative IPSS\u2010QOL score and post\u2010operative MUCP were significant predictive factors for de novo OAB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The incidence rate of de novo OAB after RARP was about 40%, and seemed unexpectedly high. Decreased urethral function was significantly related to de novo OAB after surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.23556","type":"journal-article","created":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T19:46:36Z","timestamp":1523389596000},"page":"2008-2014","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["De novo overactive bladder after robot\u2010assisted laparoscopic radical prostatectomy"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7823-2600","authenticated-orcid":false,"given":"Yoshihisa","family":"Matsukawa","sequence":"first","affiliation":[{"name":"Department of Urology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yashushi","family":"Yoshino","sequence":"additional","affiliation":[{"name":"Department of Urology Nagoya University Graduate School of 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