{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:17:31Z","timestamp":1790111851652,"version":"4.0.1"},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T00:00:00Z","timestamp":1535673600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>The Multiple Sclerosis Intimacy and Sexuality Questionnaire (MSISQ\u201015) evaluates symptoms of sexual dysfunction in patients with multiple sclerosis (MS). The objective of this study was to provide and validate a Dutch version of the MSISQ\u201015 in patients with neurological disease such as MS and spinal cord injury (SCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The linguistic validation process of the original English MSISQ\u201015 into Dutch was performed according to standardized guidelines. Sexually active patients with MS or spinal cord disorders, including SCI and cauda equine syndrome, who visited a tertiary urology center or a rehabilitation center completed the MSISQ\u201015, Pelvic Organ Prolapse\/Urinary Incontinence Sexual Questionnaire (PISQ\u201012) in women, or International Index of Erection Function (IIEF\u201015) in men at baseline (test) and 2 weeks later (retest). A reference group recruited from a general medical practice completed the questionnaires once. Data were analyzed for measurement properties.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010three patients with MS, 49 patients with spinal cord disorder, and 50 references were included. Content validity was adequate. Internal consistency (Cronbach's alpha &gt;0.8) and reproducibility (intraclass correlation coefficient &gt;0.8) of the MSISQ\u201015 were excellent. Patients\u2019 MSISQ\u201015 scores were correlated with severity of symptoms of sexual dysfunction measured by PISQ\u201012 or IIEF\u201015 and confirmed positive rating for criterion validity. MSISQ\u201015 scores in patients were higher than in references (on a scale of 15\u201075: 38.9\u2009\u00b1\u200911.4 vs 21.1\u2009\u00b1\u20095.4; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), indicating good construct validity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Dutch MSISQ\u201015 is a reliable and valid measure to evaluate symptoms of sexual dysfunction in patients with MS or with SCI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23804","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T09:48:20Z","timestamp":1535708900000},"page":"2867-2874","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The Multiple Sclerosis Intimacy and Sexuality Questionnaire (MSISQ\u201015): Validation of the Dutch version in patients with multiple sclerosis and spinal cord injury"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7508-0215","authenticated-orcid":false,"given":"Toscane C.","family":"Noordhoff","sequence":"first","affiliation":[{"name":"Department of Urology Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen R.","family":"Scheepe","sequence":"additional","affiliation":[{"name":"Department of Urology Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisette A.","family":"'t Hoen","sequence":"additional","affiliation":[{"name":"Department of Urology Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tebbe A. R.","family":"Sluis","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Rijndam Rehabilitation Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertil F. M.","family":"Blok","sequence":"additional","affiliation":[{"name":"Department of Urology Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,31]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60238-4"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/0092623X.2013.869777"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2016.06.009"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005421627154"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458512471876"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsm.12531"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/0004-282X20150078"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-003-1063-2"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-015-2692-y"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00238-0"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(93)90142-N"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2006.03.012"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2005.10.015"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1179\/204577211X13207446293695"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1201\/b18585"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23168"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-017-0280-9"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.23804","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.23804","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T08:55:51Z","timestamp":1694681751000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.23804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,31]]},"references-count":18,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1002\/nau.23804"],"URL":"https:\/\/doi.org\/10.1002\/nau.23804","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,31]]},"assertion":[{"value":"2018-05-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}