{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T12:41:42Z","timestamp":1784292102523,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T00:00:00Z","timestamp":1540252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To report the very long\u2010term functional outcomes of augmentation cystoplasty (AC) in adult spina bifida patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All consecutive adult spina bifida patients who underwent AC between 1991 and 2008 were enrolled. Early postoperative complications (Clavien\u2010Dindo classification) and long\u2010term outcomes (voiding modalities, urodynamic parameters, renal function, continence, and quality of life) were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010eight patients with a median age of 20 years (IQR 17\u201025) were included. They all underwent AC with a supratrigonal cystectomy (SC). The median follow\u2010up was 13.6 years (IQR 6\u201016.5). Thirteen early postoperative complications (12 grade I\u2010II, 1 grade III) were observed in 11 patients (39%). Eight patients (29%) had upper urinary tract infections managed with antibiotics, with 2 patients requiring ureteral stents. Bladder stones occurred in 2 patients (7%) and were managed with endoscopy and cystostomy. One bladder perforation was reported. One bladder cancer was observed 26 years after surgery. Creatinine clearance and all urodynamic parameters were significantly improved post\u2010operatively. The overall complication and reoperation rates were 57% and 14%, respectively. At last follow up, the continence rate was 71% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200920), with 93% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200926) performing intermittent self\u2010catheterization. Quality of life was improved for 71% of patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In adult spina bifida population, AC is a high\u2010risk procedure with an overall complication rate of 57% and a reoperation rate of 14%. However, AC is beneficial to the overall health of the patients since it provides a satisfying continence rate, an improvement of quality of life, and long\u2010term protection of the upper urinary tract.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.23857","type":"journal-article","created":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T08:39:36Z","timestamp":1540283976000},"page":"330-337","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Long\u2010term functional outcomes of augmentation cystoplasty in adult spina bifida patients: A single\u2010center experience in a multidisciplinary team"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0212-2840","authenticated-orcid":false,"given":"Marie\u2010Aim\u00e9e","family":"Perrouin\u2010Verbe","sequence":"first","affiliation":[{"name":"Piti\u00e9\u2010Salp\u00e9tri\u00e8re Academic Hospital Department of Urology Sorbonne University Assistance Publique\u2010H\u00f4pitaux de Paris Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscilla","family":"L\u00e9on","sequence":"additional","affiliation":[{"name":"Piti\u00e9\u2010Salp\u00e9tri\u00e8re Academic Hospital Department of Urology Sorbonne University Assistance Publique\u2010H\u00f4pitaux de Paris Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Denys","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Raymond Poincar\u00e9 Hospital Garches France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Mongiat\u2010Artus","sequence":"additional","affiliation":[{"name":"Department of Urology Saint\u2010Louis Hospital Paris 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