{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T22:11:57Z","timestamp":1789596717106,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T00:00:00Z","timestamp":1555286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Urogyn BV"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To assess the patients' median\u2010accepted threshold of cure rate for urethral bulking agent (UBA) treatment compared to mid\u2010urethral sling (MUS) surgery for treatment of female stress urinary incontinence (SUI). Secondly, to determine the correlation between treatment trade\u2010off point and patient characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Women older than 18 years, with predominant SUI, seeking treatment, underwent a structured interview. The treatment trade\u2010off point was determined in scenario one: UBA vs transobturator standard MUS surgery (SMUS) performed under general\/spinal anesthesia with one\u2010night hospital stay, and scenario 2: UBA compared to single\u2010incision MUS surgery (SIMS) performed under local analgesia (with sedation) in a daycare setting. The treatment trade\u2010off point was assessed by decreasing the cure rate of UBA from 85% to 10% with steps of 2% until the patient's treatment preference switched to SMUS\/SIMS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and five patients were interviewed. Mean age was 52 years (SD, \u00b113.4). The median trade\u2010off point for scenarios 1 and 2 was 79% (interquartile range [IQR]: 69, 85) and 85% (IQR: 71, 85), respectively. Patients with longer duration of SUI symptoms were willing to trade more efficacy to prefer UBA treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with SUI are willing to trade a lower cure rate to prefer UBA over SMUS to avoid hospitalization and general anesthesia. When SIMS is performed in a daycare setting under local analgesia, the majority of patients with SUI are of the opinion that cure rates of UBA should be at least as high as SIMS to be worth considering. The treatment preference is not strongly correlated with the patients' characteristics.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.23997","type":"journal-article","created":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T04:28:40Z","timestamp":1555388920000},"page":"1384-1391","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["How cure rates drive patients' preference for urethral bulking agent or mid\u2010urethral sling surgery as therapy for stress urinary incontinence"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8220-9742","authenticated-orcid":false,"given":"Fenne M.","family":"Casteleijn","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC University of Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa 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W.R.","family":"Roovers","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC University of Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,15]]},"reference":[{"key":"e_1_2_6_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-017-3314-7"},{"key":"e_1_2_6_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000148"},{"key":"e_1_2_6_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-017-3362-z"},{"key":"e_1_2_6_1_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/851823"},{"key":"e_1_2_6_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-1834-8"},{"key":"e_1_2_6_1_7_1","first-page":"Cd003881","article-title":"Urethral injection therapy for urinary incontinence in women","volume":"7","author":"Kirchin V","year":"2017","journal-title":"Cochrane Database Syst 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