{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:55:07Z","timestamp":1761562507172,"version":"3.37.3"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,5,18]],"date-time":"2019-05-18T00:00:00Z","timestamp":1558137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To evaluate the adjustable single\u2010incision sling (Ajust\u00ae) in the treatment of stress urinary incontinence (SUI), when placed under conscious sedation with local infiltration, using the cough test during surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this multicenter observational study, 90 women who had moderate to severe SUI, were asked to have the Ajust\u00ae procedure performed under sedation with local infiltration with levobupivacain. This allowed for a perioperative cough test to adjust the sling to the urethra till continence was reached. The primary outcome of the study was subjective cure of stress incontinence at 1 year follow up. Secondary objectives were objective and subjective improvement, complications during and after the procedure, and postoperative pain scores. These results were compared with the results of a historical control group of 96 patients who received their Ajust\u00ae under general or regional (spinal) anesthesia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 6 weeks and 12 months, there were no statistical significant differences in the results for subjective cure (83.6% and 71.6% sedation group, 88.4% and 77.2% general\/regional anesthesia group), objective cure (96% and 86.9% sedation group, 88.1% and 91.8% general\/regional anesthesia group), de novo urgency (10.5% and 6.7% sedation group, 7.1% and 24.1% general\/regional anesthesia group) and the patients global impression of improvement (96% and 89.2% sedation group, 91.4% and 84.4% general\/regional anesthesia group).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The performance of a cough test during the placement of an adjustable single\u2010incision sling for the treatment of SUI does not affect the functional outcome, and is therefore not necessary.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24027","type":"journal-article","created":{"date-parts":[[2019,5,18]],"date-time":"2019-05-18T16:50:12Z","timestamp":1558198212000},"page":"1632-1639","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A prospective observational cohort study of the Ajust\u00ae single incision sling performed under conscious sedation with local infiltration"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9968-2862","authenticated-orcid":false,"given":"Marian K.","family":"Engberts","sequence":"first","affiliation":[{"name":"Departments of Reproductive Medicine and Gynecology and Anesthesiology Isala Zwolle"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karlijn J.","family":"Schweitzer","sequence":"additional","affiliation":[{"name":"University Medical Center Utrecht\/Bergman Clinics Utrecht"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo W. F.","family":"van Eijndhoven","sequence":"additional","affiliation":[{"name":"Departments of Reproductive Medicine and Gynecology and Anesthesiology Isala Zwolle"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geert\u2010Jan","family":"Cromheecke","sequence":"additional","affiliation":[{"name":"University Medical Center Utrecht\/Bergman Clinics Utrecht"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry R.","family":"Naber","sequence":"additional","affiliation":[{"name":"Departments of Reproductive Medicine and Gynecology and Anesthesiology Isala Zwolle"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Huub van der Vaart","sequence":"additional","affiliation":[{"name":"University Medical Center Utrecht\/Bergman Clinics Utrecht"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,18]]},"reference":[{"key":"e_1_2_7_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01902378"},{"key":"e_1_2_7_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01268.x"},{"key":"e_1_2_7_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-010-1254-6"},{"key":"e_1_2_7_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-1740-0"},{"key":"e_1_2_7_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2013.07.041"},{"key":"e_1_2_7_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-012-2669-8"},{"key":"e_1_2_7_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2012.06.022"},{"key":"e_1_2_7_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2013.02.080"},{"key":"e_1_2_7_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.purol.2013.04.001"},{"key":"e_1_2_7_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12388"},{"key":"e_1_2_7_1_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10471.x"},{"key":"e_1_2_7_1_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000604"},{"key":"e_1_2_7_1_14_1","unstructured":"AssassaRPAjust 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