{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T02:12:57Z","timestamp":1782785577130,"version":"3.54.5"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T00:00:00Z","timestamp":1568246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>We desire to evaluate whether utilization of \u22643\u2009V (new experimental approach) vs the traditional four or more volts for lead motor response during stage 1 sacral neuromodulation may impart an improvement in voiding and pain parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An observational, retrospective, double cohort review was conducted of 179 female patients who experienced medically recalcitrant interstitial cystitis (IC) or bladder pain syndrome (BPS) between January 2002 and January 2013. Group A included 105 women with a motor response of \u22643\u2009V; group B was comprised of 65 women with a motor response at \u22654\u2009V for medically recalcitrant IC or BPS. Patients completed a 3\u2010day pre\u2010 and postoperative voiding diary, visual analog pain (VAP) scale, pain urgency frequency (PUF), and Patient Global Impression of Improvement (PGI\u2010I) questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean (standard deviation) follow\u2010up in months was 120.1\u2009\u00b1\u200933.3 in group A and 116.3\u2009\u00b1\u200929.2 in group B (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.45). A successful conversion from stage 1 to stage 2 showed statistically significant improvement for group A compared with group B (95.4% vs 73.8% conversion rate;\u00a0<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). The success rate also favored group A, with 87.6% success compared with 66.2% for group B (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.002). Group A mean postoperative VAP scores improved over group B with 3.3\u2009\u00b1\u20091.2 compared with 5.0\u2009\u00b1\u20090.8 (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). Group A mean postoperative PUF scores were 10.2\u2009\u00b1\u20092.7 and group B 14.7\u2009\u00b1\u20093.5, (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the \u22643\u2009V patient cohort, a compelling, significant statistical improvement was noted in most clinical voiding parameters, including the VAP, PGI\u2010I, and performance questionnaires.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24123","type":"journal-article","created":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T12:28:33Z","timestamp":1568291313000},"page":"2233-2241","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Improving clinical outcomes with lower motor voltage (\u22643\u2009V) during stage 1 sacral neuromodulation for interstitial cystitis or bladder pain syndrome"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7105-2340","authenticated-orcid":false,"given":"Serge P.","family":"Marinkovic","sequence":"first","affiliation":[{"name":"Detroit Medical Center\/Harper Hospital  Detroit 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