{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T17:20:26Z","timestamp":1786555226367,"version":"build-2736575974"},"reference-count":69,"publisher":"Wiley","issue":"S5","license":[{"start":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T00:00:00Z","timestamp":1575936000000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This paper summarises the discussion in a think tank at the International Consultation on Incontinence\u2010Research Society (ICI\u2010RS) 2018 about the treatment of bladder pain syndrome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To review the treatments of bladder pain syndrome from behavioural treatments to surgical interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Review the literature in the light of the think tank discussions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All guidelines recommend different levels of treatment starting with conservative behavioral treatments then introducing oral treatments followed by intravesical instillations. If these treatments fail then more invasive treatments such as botulinum toxin injections, neuromodulation, or surgery could be suggested.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Unfortunately for all treatments, the numbers are limited and, therefore, the evidence base is not strong. Further suggestions for research are suggested.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24245","type":"journal-article","created":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T16:06:36Z","timestamp":1575993996000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["How can we improve the diagnosis and management of bladder pain syndrome? Part 2:ICI\u2010RS 2018"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4775-7495","authenticated-orcid":false,"given":"Vik","family":"Khullar","sequence":"first","affiliation":[{"name":"Department of Urogynaecology, St Mary's Hospital Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3914-8147","authenticated-orcid":false,"given":"G. Alessandro","family":"Digesu","sequence":"additional","affiliation":[{"name":"Department of Urogynaecology, St Mary's Hospital Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2102-9254","authenticated-orcid":false,"given":"Nikolaus","family":"Veit\u2010Rubin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4679-0506","authenticated-orcid":false,"given":"Arun","family":"Sahai","sequence":"additional","affiliation":[{"name":"Department of Urology, Guy's Hospital, MRC Centre for Transplantation King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1953-7441","authenticated-orcid":false,"given":"Mohammad Sajjad","family":"Rahnama'i","sequence":"additional","affiliation":[{"name":"Urology Department Uniklinik RWTH Aachen Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3387-3524","authenticated-orcid":false,"given":"Tufan","family":"Tarcan","sequence":"additional","affiliation":[{"name":"Department of Urology Marmara University School of Medicine Istanbul Turkey"},{"name":"Department of Urology Ko\u00e7 University School of Medicine Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9444-4662","authenticated-orcid":false,"given":"Christopher","family":"Chermansky","sequence":"additional","affiliation":[{"name":"Department of Urology University of Pittsburgh School of Medicine Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9838-9178","authenticated-orcid":false,"given":"Roger","family":"Dmochowski","sequence":"additional","affiliation":[{"name":"Department of Urologic Surgery Vanderbilt University Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,10]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"e46","article-title":"Management of bladder pain syndrome: green\u2010top guideline no: 70","volume":"124","author":"Tirlapur SABJCCL","year":"2016","journal-title":"Br J Obstet Gynaecol"},{"key":"e_1_2_10_3_1","first-page":"2203","volume-title":"Incontinence","author":"Hanno P","year":"2017"},{"key":"e_1_2_10_4_1","unstructured":"EngelerDBABJ CottrellAMEUA guidelines on Chronic Pelvic Pain2018."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.3786"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2018.05.027"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2009.02326.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2019.01.012"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2017.02.053"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.4505"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.12.106"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000132388.54703.4d"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22407"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(90)80116-5"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000083020.06212.3d"},{"key":"e_1_2_10_16_1","first-page":"1","article-title":"Efficacy of pentosan polysulfate for the treatment of interstitial cystitis\/bladder pain syndrome: results of a systematic review of randomized controlled trials","volume":"35","author":"Ophoven A","year":"2019","journal-title":"Curr Med Res Opin"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.08.170"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.09.036"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2001.02031.x"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.02.050"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000181808.45786.84"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67520-9"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2012.07.035"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2000.00490.x"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)61950-5"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.5213\/inj.2010.14.4.256"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.5213\/inj.2013.17.2.78"},{"key":"e_1_2_10_28_1","first-page":"CD006113","article-title":"Intravesical treatments for painful bladder syndrome\/interstitial cystitis","author":"Dawson TE","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(96)00322-6"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)38437-9"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-007-0515-5"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22256"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001200050406"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)00845-1"},{"key":"e_1_2_10_35_1","first-page":"225","article-title":"Chronic pelvic pain of bladder origin: epidemiology, pathogenesis, and quality of life","volume":"49","author":"Burkman RT","year":"2004","journal-title":"J Reprod Med"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.08028.x"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00181-7"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-015-2890-7"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.13118"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.01.086"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpuro1124"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2007.07312.x"},{"issue":"225","key":"e_1_2_10_43_1","first-page":"e213","article-title":"Differences in mast cell infiltration, E\u2010cadherin, and zonula occludens\u20101 expression between patients with overactive bladder and interstitial cystitis\/bladder pain syndrome","volume":"80","author":"Liu HT","year":"2012","journal-title":"Urology"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11466.x"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.05.007"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23493"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.06.073"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1159\/000087173"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.12833"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08495.x"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22760"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.2174\/156720110793566317"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.02.031"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpuro0034"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins7104283"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23475"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.10.018"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.14399"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2017.11.002"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2010.09697.x"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-11062-x"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23493"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2007.07082.x"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)63726-1"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.12320"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2554-6"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.05.028"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365599.2012.669789"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.3109\/21681805.2013.840334"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-017-3307-6"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnau.24245","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.24245","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/nau.24245","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.24245","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T01:22:45Z","timestamp":1694136165000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.24245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":69,"journal-issue":{"issue":"S5","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1002\/nau.24245"],"URL":"https:\/\/doi.org\/10.1002\/nau.24245","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"2019-05-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}