{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T07:31:18Z","timestamp":1778657478316,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T00:00:00Z","timestamp":1581984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>To evaluate outcomes following urethral Macroplastique (MPQ) injection in women with stress urinary incontinence (SUI) following suburethral sling removal (SSR) for synthetic sling complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Following Institutional Review Board approval, charts of non\u2010neurogenic women with SUI after SSR who underwent MPQ injection(s) and had at least 6 months minimum follow\u2010up were reviewed from a prospectively maintained database. Demographic data, questionnaire (Urogenital Distress Inventory\u20106 [UDI\u20106] and Quality of Life) scores, and pad usage were recorded. Patients were followed with repeat questionnaires and three\u2010dimensional ultrasound evaluating MPQ volume. Success following MPQ was defined as a composite score of a UDI\u20106 question 3 score of 0 to 1 at last visit and no additional anti\u2010incontinence therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2011 to 2018, 70 women with mean age 62.7 years met study criteria. At a mean follow\u2010up of 46.4\u2009\u00b1\u20091.5 months, the success rate after the first MPQ injection was 46%. Following a repeat MPQ injection when indicated, the overall success rate for the entire cohort was 69%. Despite the objective failure, the majority of patients reported subjective improvement (83%) and reduced pad usage (78%). On multivariate analysis: age, body mass index, previous hysterectomy, hormone replacement therapy, type of sling removed and baseline urodynamics (UDS) parameters were not predictors of MPQ failure. Higher parity was a predictor of MPQ failure (hazard ratio\u2009=\u20091.980; <jats:italic>P<\/jats:italic>\u2009=\u2009.032).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MPQ injection is a durable and effective management option for SUI following SSR, although a second injection may be required to achieve the desired success.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24321","type":"journal-article","created":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T12:31:47Z","timestamp":1582029107000},"page":"994-1001","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Outcomes of Macroplastique injections for stress urinary incontinence after suburethral sling removal"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2081-6416","authenticated-orcid":false,"given":"Dayron","family":"Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Carroll","sequence":"additional","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feras","family":"Alhalabi","sequence":"additional","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1495-0448","authenticated-orcid":false,"given":"Maude","family":"Carmel","sequence":"additional","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7612-2042","authenticated-orcid":false,"given":"Philippe 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