{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:52:22Z","timestamp":1790707942438,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T00:00:00Z","timestamp":1583971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The primary aim of this study was to assess the relationship between a strong desire to void (SDV) and rectal sensory function in patients with multiple sclerosis (PwMS) and anorectal disorders. The secondary aim was to identify clinical, urodynamic or manometric factors associated with greater rectal sensory function impairment in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty PwMS (mean age 49.2\u2009\u00b1\u200910.9 years) with anorectal disorders (constipation and\/or fecal incontinence) participated in this observational study. Rectal sensory parameters during anorectal manometry were recorded at a strong desire to void and after urination (PV, post\u2010void). The primary outcome was the desire to defecate volume. Secondary outcomes were first perception and maximum tolerated threshold volumes, presence and modulation of recto\u2010anal inhibitory reflex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean desire to defecate volume was 125\u2009\u00b1\u200959\u2009mL at SDV and 104\u2009\u00b1\u200964\u2009mL at PV (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). The mean maximum tolerated volume was 167\u2009\u00b1\u200961\u2009mL at SDV vs 141\u2009\u00b1\u200964\u2009mL after urination (<jats:italic>P<\/jats:italic>\u2009=\u2009.01). The other parameters were not different between SVD and PV conditions. No predictive factors for greater impairment of rectal sensory function were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study suggests a relationship between bladder sensation and thus bladder capacity, and rectal sensory function in PwMS and with anorectal disorders.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24330","type":"journal-article","created":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T16:54:11Z","timestamp":1584032051000},"page":"1129-1136","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Relationship between desire to void and bladder capacity and rectal sensory function in patients with multiple sclerosis and anorectal disorders"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4603-2422","authenticated-orcid":false,"given":"Camille","family":"Pouyau","sequence":"first","affiliation":[{"name":"Sorbonne Universit\u00e9, GRC 001, GREEN Groupe de Recherche Clinique en Neuro\u2010Urologie, AP\u2010HP, H\u00f4pital Tenon  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Grasland","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, GRC 001, GREEN Groupe de Recherche Clinique en Neuro\u2010Urologie, AP\u2010HP, H\u00f4pital Tenon  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Leroux","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, GRC 001, GREEN Groupe de Recherche Clinique en Neuro\u2010Urologie, AP\u2010HP, H\u00f4pital Tenon  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8260-3678","authenticated-orcid":false,"given":"Camille","family":"Chesnel","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, GRC 001, GREEN Groupe de Recherche Clinique en 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