{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:11:55Z","timestamp":1792782715821,"version":"4.5.0"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T00:00:00Z","timestamp":1587945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Axonics Modulation Technologies","id":[{"id":"https:\/\/ror.org\/01ra0cf82","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Sacral neuromodulation (SNM) is a guideline\u2010recommended treatment for voiding dysfunction including urgency, urge incontinence, and nonobstructive retention as well as fecal incontinence. The Axonics\u00ae System is a miniaturized, rechargeable SNM system designed to provide therapy for at least 15 years, which is expected to significantly reduce revision surgeries as it will not require replacement as frequently as the non\u2010rechargeable SNM system. The ARTISAN\u2010SNM study is a pivotal study designed to treat patients with urinary urgency incontinence (UUI). Clinical results at 1\u2010year are presented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 129 eligible UUI patients were treated. All participants were implanted with a quadripolar tined lead and neurostimulator in a single procedure. Efficacy data were collected using a 3\u2010day bladder diary, a validated quality of life questionnaire (ICIQ\u2010OABqol), and a participant satisfaction questionnaire. Therapy responders were defined as participants with \u226550% reduction in UUI episodes compared to baseline. Data were analyzed on all 129 participants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At 1 year, 89% of the participants were therapy responders. The average UUI episodes per day reduced from 5.6\u2009\u00b1\u20090.3 at baseline to 1.4\u2009\u00b1\u20090.2. Participants experienced an overall clinically meaningful improvement of 34 points on the ICIQ\u2010OABqol questionnaire. All study participants (100%) were able to recharge their device at 1 year, and 96% of participants reported that the frequency and duration of recharging was acceptable. There were no serious device\u2010related adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Axonics System is safe and effective at 1 year, with 89% of participants experiencing clinically and statistically significant improvements in UUI symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.24376","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T16:03:07Z","timestamp":1588003387000},"page":"1482-1488","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["One\u2010year outcomes of the ARTISAN\u2010SNM study with the Axonics System for the treatment of urinary urgency incontinence"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9512-7431","authenticated-orcid":false,"given":"Kevin","family":"Benson","sequence":"first","affiliation":[{"name":"Sanford Hospital  Sioux Falls South Dakota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"McCrery","sequence":"additional","affiliation":[{"name":"Adult and Pediatric Urology and Urogynecology  Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Taylor","sequence":"additional","affiliation":[{"name":"Taylor Surgical Arts  Harrison Arkansas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osvaldo","family":"Padron","sequence":"additional","affiliation":[{"name":"Florida Urology Partners  Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9354-7395","authenticated-orcid":false,"given":"Bertil","family":"Blok","sequence":"additional","affiliation":[{"name":"Department of Urology Erasmus MC  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"de Wachter","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Antwerpen  Edegem Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Pezzella","sequence":"additional","affiliation":[{"name":"Southern Urogynecology  West Columbia South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Gruenenfelder","sequence":"additional","affiliation":[{"name":"Orange County Urology Associates  Laguna Hills California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahreen","family":"Pakzad","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospital  Marylebone London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Aimee","family":"Perrouin\u2010Verbe","sequence":"additional","affiliation":[{"name":"Department of Urology CHU de Nantes Hotel Dieu  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Van Kerrebroeck","sequence":"additional","affiliation":[{"name":"Department of Urology Maastricht University Medical Centre  Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Mangel","sequence":"additional","affiliation":[{"name":"MetroHealth  Cleveland 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