{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T12:28:35Z","timestamp":1770812915145,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T00:00:00Z","timestamp":1605657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study is to determine the risk factors predicting upper urinary tract (UUT) deterioration in children with spinal cord injury (SCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of 108 children with SCI who were referred to our unit between 1996 and 2018 were retrospectively reviewed. The data included general patient demographics, SCI characteristics, bladder management methods, presence of urinary tract infection, radiological evaluation of the UUT and lower urinary tract (LUT), and videourodynamic\u00a0findings. The receiver operating characteristic (ROC) curve analysis was performed to determine the cutoff values of the maximum detrusor pressure during filling and the bladder volume ratio (BVR) for predicting UUT deterioration. Multivariate analyses were used to determine the risk factors predicting UUT deterioration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complete data were available for 76 children. The median patient age was 15 years (2\u201317). The leading causes of SCI were motor vehicle accidents (44%) and fall (33%). UUT deterioration was identified in 33 patients (43%). Iatrogenic SCI etiology, abnormal radiological LUT findings, and detrusor pressures greater than 70\u2009cmH<jats:sub>2<\/jats:sub>O were found to be independent risk factors for UUT deterioration using regression analysis. In addition, ROC analysis revealed that a BVR less than 0.7 was the cutoff value for UUT deterioration in children with SCI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Abnormal radiological LUT findings, iatrogenic SCI etiology, detrusor pressure greater than 70\u2009cmH<jats:sub>2<\/jats:sub>O, and a BVR less than 0.7 were independent risk factors for UUT deterioration in children with SCI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24580","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T18:34:58Z","timestamp":1605724498000},"page":"435-442","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Risk factors predicting upper urinary tract deterioration in children with spinal cord injury"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0540-2693","authenticated-orcid":false,"given":"B\u00fclent","family":"\u00d6nal","sequence":"first","affiliation":[{"name":"Department of Urology, Cerrahpasa School of Medicine Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1010-1529","authenticated-orcid":false,"given":"Elif A.","family":"K\u0131rl\u0131","sequence":"additional","affiliation":[{"name":"Department of Urology, Cerrahpasa School of Medicine Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5115-753X","authenticated-orcid":false,"given":"Berin","family":"Sel\u00e7uk","sequence":"additional","affiliation":[{"name":"Department of Urology, Cerrahpasa School of Medicine Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0631-3791","authenticated-orcid":false,"given":"Derya","family":"Bu\u011fdayc\u0131","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Istanbul Physical Medicine and Rehabilitation Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5815-6700","authenticated-orcid":false,"given":"G\u00fcnay","family":"Can","sequence":"additional","affiliation":[{"name":"Department of Public Health, Cerrahpasa School of Medicine Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4668-3359","authenticated-orcid":false,"given":"B\u00fclent","family":"\u00c7etinel","sequence":"additional","affiliation":[{"name":"Department of Urology, Cerrahpasa School of Medicine Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000135402.56109.cf"},{"key":"e_1_2_8_3_1","first-page":"46","volume-title":"EUA\/ESPU Guidelines on Paediatric Urology","author":"Radmayr C"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.03.107"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2005.05.004"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.1994.127"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22751"},{"key":"e_1_2_8_8_1","first-page":"1","article-title":"Micturation in infants and children with normal urinary tract. 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