{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T17:05:33Z","timestamp":1792861533212,"version":"4.5.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,8]],"date-time":"2020-12-08T00:00:00Z","timestamp":1607385600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the management methods of female urethral stricture (FUS) and analyze the outcomes of surgical treatments. A meta\u2010analysis was done in an attempt to identify the best approach of urethroplasty and the graft\u2010of\u2010choice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A systematic search of Pubmed\/Medline and Embase databases was performed according to the Preferred Reporting Items For Systematic Review And Meta\u2010Analysis statement, for articles reporting on FUS management in the last decade. The Newcastle\u2010Ottawa scale was used\u00a0to assess the quality of 28 included non\u2010randomized studies. The data on FUS management was summarized and pooled success rates (taken as symptom improvement and no need for further instrumentation) were compared. The secondary outcome was to establish a diagnostic modality of choice and define a \u201csuccessful\u2010outcome\u201d\u00a0of repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The outcome was separately reported for 554 women undergoing surgical intervention for FUS in the literature. The criteria defining FUS were varied. A combination of tests was used for diagnosis as none was singularly conclusive. A total of 301 patients had previous urethral instrumentations. The pooled success rate of urethral dilatation (234 women) was 49% at a mean follow\u2010up of 32 months; flap urethroplasty (108 cases) was 92% at a mean follow\u2010up of 42 months; buccal mucosal graft (BMG) urethroplasty (133 cases) was 89% at a mean follow\u2010up of 19 months; vaginal graft augmentation (44 cases) was 87% at a mean follow\u2010up of 15 months; and labial graft reconstruction (19 cases) was 89% at a mean follow\u2010up of 18.4 months. The dorsal approach of graft augmentation met with 88% (95% confidence interval [CI] 0.79\u20130.95) success compared with\u00a095% (95% CI 0.86\u20131) for the ventral approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>FUS is a rare condition\u00a0requiring a meticulous diagnostic workup using multiple tests. All urethroplasties have shown better pooled success rates (86%\u201393%) compared with dilatation (49%). BMG is equally effective as vaginal graft urethroplasty.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.24584","type":"journal-article","created":{"date-parts":[[2020,12,8]],"date-time":"2020-12-08T05:22:15Z","timestamp":1607404935000},"page":"65-79","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Deciphering the enigma of female urethral strictures: A systematic review and meta\u2010analysis of management modalities"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4945-1913","authenticated-orcid":false,"given":"Indira","family":"Sarin","sequence":"first","affiliation":[{"name":"Department of Urology All India Institute of Medical Sciences  Rishikesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tushar A.","family":"Narain","sequence":"additional","affiliation":[{"name":"Department of Urology All India Institute of Medical Sciences  Rishikesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas K.","family":"Panwar","sequence":"additional","affiliation":[{"name":"Department of Urology All India Institute of Medical Sciences  Rishikesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajeet S.","family":"Bhadoria","sequence":"additional","affiliation":[{"name":"Department of Community and Family Medicine All India Institute of Medical Sciences  Rishikesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard B.","family":"Goldman","sequence":"additional","affiliation":[{"name":"Department of Urology, Glickman Urologic and Kidney Institute, Cleveland Clinic Lerner College of Medicine  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8040-9935","authenticated-orcid":false,"given":"Ankur","family":"Mittal","sequence":"additional","affiliation":[{"name":"Department of Urology All India 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