{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:40:29Z","timestamp":1790732429953,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T00:00:00Z","timestamp":1608076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aims to investigate the efficacy of transcutaneous tibial nerve home stimulation for overactive bladder (OAB) in women with Parkinson's disease (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The current study is a prospective, randomized, double\u2010blind, sham\u2010controlled trial. Home intervention was carried out and\u00a0assessments were conducted at a tertiary hospital in South Brazil. Women with PD and OAB symptoms were included in the study. Patients were randomly divided into two groups: (1) stimulation and (2) sham. Both groups underwent intervention at home for 12 weeks. Patients were evaluated at baseline and at 12 weeks (end of intervention),\u00a030\u2010 and 90\u2010day follow\u2010up. The primary outcome was the mean reduction in the number of\u00a0urgency incontinence episodes, and secondary outcomes included daytime and nighttime urinary frequency, urinary urgency episodes, use of pad (reported in a 24\u2010h bladder diary), OAB\u2010V8 and\u00a0King's Health Questionnaire scores, and maintenance\u00a0of symptom relief after discontinuation of the intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 30 consecutive patients completed the study (15\/group). The stimulation group showed a reduction in nighttime urinary frequency (0.9\u2009\u00b1\u20090.6), urinary urgency (1.0\u2009\u00b1\u20091.2), urgency incontinence episodes (0.5\u2009\u00b1\u20090.6), use of pads (1.3\u2009\u00b1\u20091.2), and OAB\u2010V8 (1.3\u2009\u00b1\u20091.2)\u00a0and King's Health Questionnaire scores. In a 30\u2010day and 90\u2010day follow\u2010up, 8 (53.3%) and 5 (33.3%) stimulation patients, respectively, reported full\u00a0maintenance of symptom relief after discontinuation of the intervention. Stimulation patients presented a statistically significant improvement of symptoms as compared with sham patients (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Transcutaneous tibial nerve home stimulation can be used in clinical practice as an effective nonpharmacological resource for the reduction of OAB symptoms in women with PD, and the resulting relief seems to persist\u00a0in the follow\u2010up (30 and 90 days).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.24595","type":"journal-article","created":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T21:10:10Z","timestamp":1608239410000},"page":"538-548","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Transcutaneous tibial nerve home stimulation for overactive bladder in women with Parkinson's disease: A randomized clinical trial"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6647-7934","authenticated-orcid":false,"given":"Tatiane G.","family":"Araujo","sequence":"first","affiliation":[{"name":"School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS)  Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana P.","family":"Schmidt","sequence":"additional","affiliation":[{"name":"School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS)  Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0345-7845","authenticated-orcid":false,"given":"Paulo R. S.","family":"Sanches","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Department Hospital de Cl\u00ednicas de Porto Alegre (HCPA)  Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danton P.","family":"Silva Junior","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Department Hospital de Cl\u00ednicas de Porto Alegre (HCPA)  Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2950-7211","authenticated-orcid":false,"given":"Carlos R. M.","family":"Rieder","sequence":"additional","affiliation":[{"name":"School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS)  Porto Alegre Rio Grande do Sul Brazil"},{"name":"Neurology Department Hospital de Cl\u00ednicas de Porto Alegre (HCPA)  Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3789-885X","authenticated-orcid":false,"given":"Jos\u00e9 G. 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