{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:14:18Z","timestamp":1772118858873,"version":"3.50.1"},"reference-count":53,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:00:00Z","timestamp":1611187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aims to describe the effects of radical prostatectomy (RP) on bladder function by performing a systematic review of urodynamics study findings before and after RP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This systematic review was conducted in accordance with the PRISMA guideline and registered on PROSPERO (CRD42020206844). A systematic search was conducted using PubMed, Cochrane, and Embase. Studies were included if they involved men who underwent RP and had urodynamics study performed preoperatively, postoperatively, or both. Studies that included only subgroups of patients based on symptoms were excluded. Three hundred and four articles were screened, with 20 articles included. A qualitative analysis was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The rate of baseline bladder outlet obstruction (BOO) pre\u2010RP was 19%\u201367%. All six studies with comparative data pre\u2010 and postoperatively demonstrated a decrease in the rate of patients with equivocal or clear obstruction. The baseline rates of detrusor overactivity (DO) varied widely from 11% to 61.2%. Six of eight studies with 6\u2009months or more follow\u2010up showed an improvement in the rates of DO ranging from 3.0% to 12.5%. The rate of de novo DO ranged from 0% to 54.5%. Four studies reported an increased rate of impaired bladder contractility and two of three studies showed a worsening rate of impaired bladder compliance following RP. This review is limited by the absence of level I\/II studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Urodynamics study shows that BOO is improved following RP in most patients. RP resolves DO in some patients and cause de novo DO in others. The net effect is a reduced overall rate of DO in most studies. Bladder compliance and contractility may be impaired after RP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.24606","type":"journal-article","created":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T14:33:35Z","timestamp":1611239615000},"page":"582-603","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Impact of radical prostatectomy on bladder function as demonstrated on urodynamics study\u2014A systematic review"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1955-6992","authenticated-orcid":false,"given":"Henry H.","family":"Yao","sequence":"first","affiliation":[{"name":"Department of Urology Western Health Melbourne Victoria Australia"},{"name":"Eastern Health Clinical School Monash University Melbourne Victoria Australia"},{"name":"Vesia (Alberta Bladder Centre) Southern Alberta Institute of Urology Calgary Alberta Canada"},{"name":"Department of Surgery University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2717-9085","authenticated-orcid":false,"given":"Venetia","family":"Hoe","sequence":"additional","affiliation":[{"name":"Department of Urology Western Health Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert T.","family":"Crump","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shomik","family":"Sengupta","sequence":"additional","affiliation":[{"name":"Eastern Health Clinical School Monash University Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen E.","family":"O'Connell","sequence":"additional","affiliation":[{"name":"Department of Urology Western Health Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6071-6110","authenticated-orcid":false,"given":"Kevin V.","family":"Carlson","sequence":"additional","affiliation":[{"name":"Vesia (Alberta Bladder Centre) Southern Alberta Institute of Urology Calgary Alberta Canada"},{"name":"Department of Surgery University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Baverstock","sequence":"additional","affiliation":[{"name":"Vesia (Alberta Bladder Centre) Southern Alberta Institute of Urology Calgary Alberta Canada"},{"name":"Department of Surgery University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,21]]},"reference":[{"issue":"3","key":"e_1_2_7_2_1","first-page":"S92","article-title":"The burden of prostate cancer in Canada","volume":"3","author":"Fradet Y","year":"2009","journal-title":"Can Urol Assoc J"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29210"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0b013e328329eb13"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13078"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08470.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau-20-689"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23713"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.12.060"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2018.12.003"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.02.029"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.13295"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.10.054"},{"key":"e_1_2_7_14_1","unstructured":"National Heart Lung and Blood Institute.Study Quality Assessment Tools;2020.https:\/\/www.nhlbi.nih.gov\/health-topics\/study-quality-assessment-tools. 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