{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:43:48Z","timestamp":1790963028079,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,3,14]],"date-time":"2021-03-14T00:00:00Z","timestamp":1615680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100011240","name":"Society of Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011240","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CTSA \u2010 UL1TR002240"],"award-info":[{"award-number":["CTSA \u2010 UL1TR002240"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>There is a paucity of patient reported outcome measure (PROM) data for women with urethral strictures. To address this gap, we aim to evaluate change in PROM among women who underwent surgery for a stricture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>American Urological Association Symptom Index (AUA\u2010SI) and Urogenital Distress Inventory (UDI\u20106) data from a multi\u2010institutional retrospective cohort study of women treated for urethral stricture was assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010seven women had either AUA\u2010SS or UDI\u20106 and 26 had baseline and postoperative data for either. Most women underwent urethroplasty (77%) and the majority (73%) remained stricture free at median follow\u2010up of 21 months (interquartile range [IQR] 7\u201337). The median baseline AUA\u2010SI was 21 (IQR 12\u201328) and follow\u2010up was 10 (IQR 5\u201324). After treatment, there was a median decrease of 12 (IQR \u221218 to \u22122) in AUA\u2010SI (<jats:italic>p<\/jats:italic>\u2009=\u20090.003). The median AUA Quality of life (QOL) score at baseline and follow\u2010up were 6 (IQR 4\u20136) and 3 (IQR 2\u20135), respectively. There was a median AUA\u2010QOL improvement of 2 points (\u22125,0; <jats:italic>p<\/jats:italic>\u2009=\u20090.007) from a baseline 5 (unhappy) to 3 (mixed). Median UDI\u20106 scores were 50 (IQR 33\u201375) at baseline and 17 (IQR 0\u201339), at follow\u2010up. After treatment, there was a median decrease of 19 (\u221231 to \u221211; <jats:italic>p<\/jats:italic>\u2009=\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Women with urethral strictures have severe lower urinary tract symptoms which improved after surgery. This study substantiates the claims that recognizing and treating women with urethral stricture disease greatly improves lower urinary tract symptoms and QOL.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24653","type":"journal-article","created":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T00:25:15Z","timestamp":1615767915000},"page":"986-993","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Changes in patient reported outcome measures after treatment for female urethral stricture"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6977-5280","authenticated-orcid":false,"given":"Giulia I.","family":"Lane","sequence":"first","affiliation":[{"name":"Department of Urology University of Michigan Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7958-1749","authenticated-orcid":false,"given":"Alyssa","family":"Gracely","sequence":"additional","affiliation":[{"name":"Department of Urology University of Michigan Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9188-9156","authenticated-orcid":false,"given":"Pansy","family":"Uberoi","sequence":"additional","affiliation":[{"name":"Virginia Mason Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1128-5083","authenticated-orcid":false,"given":"Una","family":"Lee","sequence":"additional","affiliation":[{"name":"Virginia Mason Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9784-2559","authenticated-orcid":false,"given":"Ariana L.","family":"Smith","sequence":"additional","affiliation":[{"name":"University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7688-4688","authenticated-orcid":false,"given":"Jennifer T.","family":"Anger","sequence":"additional","affiliation":[{"name":"Cedars\u2010Sinai Beverly Hills California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4974-6180","authenticated-orcid":false,"given":"Didi","family":"Theva","sequence":"additional","affiliation":[{"name":"Memorial Hospital Miramar Miramar Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4938-6915","authenticated-orcid":false,"given":"Jessica","family":"DeLong","sequence":"additional","affiliation":[{"name":"Eastern Virginia Medical School Norfolk Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey","family":"Kowalik","sequence":"additional","affiliation":[{"name":"Kansas University Medical Center Kansas City Kansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6215-8976","authenticated-orcid":false,"given":"Priya","family":"Padmanabhan","sequence":"additional","affiliation":[{"name":"Kansas University Medical Center Kansas City Kansas USA"},{"name":"Beaumont Hospital Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8509-5971","authenticated-orcid":false,"given":"Charles R.","family":"Powell","sequence":"additional","affiliation":[{"name":"Indiana University Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1495-0448","authenticated-orcid":false,"given":"Maude E.","family":"Carmel","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0759-3385","authenticated-orcid":false,"given":"J. 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