{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T07:34:29Z","timestamp":1771572869724,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T00:00:00Z","timestamp":1621987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To prospectively evaluate the performance of a last generation magnetic resonance imaging (MRI) device with tractography to identify the normal female urethral sphincters in terms of morphology and quantification on a large cohort of continent women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We have recorded the data of 75 continent women who underwent a diffusion tensor imaging (DTI) sequence with fiber tractography during a pelvic MR examination. Three groups of age were analyzed in terms of color fiber tracking quality and quantitative parameters (fractional anisotropy [FA] and mean diffusibility [MD]). Statistical analysis was done for the qualitative assessment using weighted kappa statistics of Cohen and for the quantitative parameters using a non\u2010parametric Kruskal\u2013Wallis test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For all cases, fiber\u2010tracking resulted in a satisfactory representation of the complexity of the orientation of the fibers. The interobserver concordance of qualitative data was substantial, calculated at 0.78 (confidence interval: 0.71\u20130.85). For FA, there was no statistically significant difference with the age between the three urethral segments (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). However, we registered a significant difference inside each group between the different segments (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), corresponding to different orientation of fibers. For MD, we have found a statistically significant difference both between levels inside each group and according the age, meaning a variation of the water mobility for each type of musculature and with age (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>DTI with fiber tractography performed on a recent MR unit is a robust method for the three\u2010dimensional visualization of the details and connections of the urethral female sphincters. Quantitative variations with age need to be considered.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24674","type":"journal-article","created":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T07:46:32Z","timestamp":1622015192000},"page":"1441-1449","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of the female bladder neck and urethra using MRI with fiber tractography: Prospective study on a large cohort of continent women"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0527-5305","authenticated-orcid":false,"given":"Catherine","family":"Roy","sequence":"first","affiliation":[{"name":"Department of Radiology University Hospital of Strasbourg  Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mickael","family":"Ohana","sequence":"additional","affiliation":[{"name":"Department of Radiology University Hospital of Strasbourg  Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aissam","family":"Labani","sequence":"additional","affiliation":[{"name":"Department of Radiology University Hospital of Strasbourg  Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thibault","family":"Tricard","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospitals of Strasbourg  Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Saussine","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospitals of Strasbourg  Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Leyendecker","sequence":"additional","affiliation":[{"name":"Department of Radiology University Hospital of Strasbourg  Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,26]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Gil VernetSMorphology and Function of the Vesico\u2010Prostato\u2010Urethral Musculature. 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