{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T07:50:45Z","timestamp":1789545045606,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To evaluate the impact of an history of radiation therapy on the outcomes of artificial urinary sphincter (AUS) implantation in male patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The charts of all patients who underwent AUS implantation for stress urinary incontinence (SUI) after prostate surgery in thirteen centers between 2004 and 2020 were retrospectively reviewed. We excluded patients with neurogenic SUI. Continence rates and incidence of complications, revision and cuff erosion were evaluated. The outcomes in irradiated men were compared to those of non irradiated men.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1277 patients who had an AUS met the inclusion criteria with a median age of 70 years, of which 437 had an history of prior radiotherapy. There was no difference in comorbidities. In irradiated patients, postoperative social continence, urethral atrophy and infection rates were respectively 75.6%, 2.4% and 9.5% and 76.8%, 5.4%, and 5.8% in nonirradiated men (respectively, <jats:italic>p<\/jats:italic>\u2009=\u20090.799, <jats:italic>p<\/jats:italic>\u2009=\u20090.128, <jats:italic>p<\/jats:italic>\u2009=\u20090.148). There were more urethral erosion in irradiated male patients. After a mean follow up of 36.8 months, the explantation free survival was poorer in irradiated patients (<jats:italic>p<\/jats:italic>\u2009=\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These data suggest that pelvic radiotherapy before AUS adversely affect device survival with and increased greater occurrence of infection\u2010erosion and therefore of explantation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24825","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T09:11:04Z","timestamp":1637745064000},"page":"332-339","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Impact of radiation therapy on artificial urinary sphincter implantation in male patients: A multicenter study"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9246-0324","authenticated-orcid":false,"given":"Jordan","family":"Mamane","sequence":"first","affiliation":[{"name":"Department of Urology University of Reims Reims France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Department of Medical Information Evaluation and Performance Troyes Hospital Troyes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre G.","family":"Lellouch","sequence":"additional","affiliation":[{"name":"Department of Plastic Reconstructive Surgery European Georges Pompidou Hospital Paris France"},{"name":"Division of Plastic and Reconstructive Surgery, and Vascularized Composite Allotransplantation Laboratory, Center for Transplantation Sciences, Massachusetts General Hospital Harvard Medical School Boston Massachusetts 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