{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:50:59Z","timestamp":1785887459312,"version":"3.56.0"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T00:00:00Z","timestamp":1638144000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To describe the oral treatments people living with interstitial cystitis\/bladder pain syndrome (IC\/BPS) are using to treat their urologic condition in the UK.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A questionnaire hyperlink encompassing current and previous medications taken for IC\/BPS with other sociodemographic and diagnostic indices was available to the Bladder Health UK website. Interested and fully consented individuals accessed and completed the survey.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 601 accessed the questionnaire of whom 173 participants responded (response rate: 28.7%) with a mean\u2009\u00b1\u2009<jats:italic>SD<\/jats:italic> O'Leary\/Sant scores of 20.12\u2009\u00b1\u20099.38. A sample size of 171 was estimated to be used in the survey. A fifth of the participants were not on any treatment at all. Amitriptyline was the most prevalent medication in use both alone and in combination. A shift in the use of unapproved (for IC\/BPS) antidepressant, smooth muscle relaxant, opioids, gabapentenoids, and antibiotics was observed in the sample. There were no significant differences between the mean (<jats:italic>SD<\/jats:italic>) O'Leary\/Sant scores of cohorts currently taking oral medications and those not taking it. More than two\u2010thirds of the participants had been diagnosed with the disease more than 5 years. Just under a half (47.4%) of participants reported a history of allergy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study provides contemporary evidence that the treatments used for managing IC\/BPS encompass a broad range of medications both recommended and not recommended by current guidelines. The latter suggests patients are willing to try novel treatments when more conventional ones are ineffective.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24840","type":"journal-article","created":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T14:09:42Z","timestamp":1638194982000},"page":"416-422","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Real world use of oral treatments in interstitial cystitis\/bladder pain syndrome in the UK: Outcome of a cross sectional study"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3109-392X","authenticated-orcid":false,"given":"Kamaluddeen","family":"Garba","sequence":"first","affiliation":[{"name":"School of Health Sciences, Southampton General Hospital University of Southampton Southampton 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