{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T01:03:20Z","timestamp":1787965400789,"version":"build-2784847793"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T00:00:00Z","timestamp":1639094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The primary aim is to explore the relationship between symptom severity and prolapse bother in women with pelvic organ prolapse (POP). The secondary aim is to determine the association between psychological variables and prolapse bother.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional observational study was conducted via online surveys assessing POP bother (visual analog scale for bother), POP symptom severity (International Consultation on Incontinence Questionnaire\u2010Vaginal Symptoms), and psychological measures of depression and anxiety (Kessler psychological distress scale [K\u201010]), catastrophizing (modified pain catastrophizing scale [mPCS]), and self\u2010efficacy (modified pain self\u2010efficacy questionnaire [mPSEQ]) in women with self\u2010reported POP. Symptom severity, bother and psychological variables were analyzed using linear regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010six women with a mean (SD) age of 42.8 (14.57) years were included in analysis. A moderate to strong positive linear relationship (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.449, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) was found between symptom severity and POP bother. Prolapse bother and psychological variables were moderately correlated, where increased K\u201010 scores (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.230, <jats:italic>p<\/jats:italic>\u2009=\u20090.001), higher mPCS scores (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.460, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and lower mPSEQ scores (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.460, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) were associated with increased POP bother. Moderate and severe catastrophizing was associated with significantly higher POP bother, with mean POP bother scores of 7.861\u2009\u00b1\u20090.45 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and 8.652\u2009\u00b1\u20090.45 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A moderate positive relationship between POP bother and symptom severity was found, with greater psychological distress and lower self\u2010efficacy associated with increasing POP bother. Women presenting with POP should be screened for psychological factors to guide management.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24842","type":"journal-article","created":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T08:21:55Z","timestamp":1639124515000},"page":"423-431","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The relationship between symptom severity, bother and psychological factors in women with pelvic organ prolapse: A cross\u2010sectional observational study"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4247-9665","authenticated-orcid":false,"given":"Katie\u2010Jay","family":"Drage","sequence":"first","affiliation":[{"name":"Masters of Clinical Physiotherapy (Continence and Women's Health) Program Curtin University Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mansi","family":"Aghera","sequence":"additional","affiliation":[{"name":"Masters of Clinical Physiotherapy (Continence and Women's Health) Program Curtin University Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phoebe","family":"MacKellar","sequence":"additional","affiliation":[{"name":"Masters of Clinical Physiotherapy (Continence and Women's Health) Program Curtin University Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhea","family":"Twentyman","sequence":"additional","affiliation":[{"name":"Masters of Clinical Physiotherapy (Continence and Women's Health) Program Curtin University Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0461-681X","authenticated-orcid":false,"given":"Angela","family":"Jacques","sequence":"additional","affiliation":[{"name":"School of Allied Health Curtin University Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6991-559X","authenticated-orcid":false,"given":"K. 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