{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:50:38Z","timestamp":1780361438078,"version":"3.54.1"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T00:00:00Z","timestamp":1642204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>An online bladder health survey was administered to national registry volunteers to: (1) determine the feasibility of using ResearchMatch for studying lower urinary tract symptoms (LUTS); (2) pilot the new, comprehensive Lower Urinary Tract Dysfunction Research Network Symptom Index\u201029 (LURN\u2010SI\u201029) and determine its ability to detect known associations with LUTS; and (3) explore novel areas of bladder health in community\u2010based women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional web\u2010based survey was administered to a random sample of ResearchMatch adult female, transgender and non\u2010binary volunteers. Participant demographics, health characteristics, the LURN\u2010SI\u201029, and LUTS\u2010related experiences were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1725 ReseachMatch volunteers with a mean age of 44.0 years completed the study and were eligible for the analysis. Participants were primarily white, cisgendered, highly educated, nulliparous, and premenopausal. The median LURN\u2010SI\u201029 score was 17 (interquartile range: 11\u201326). More than half the sample reported urinary urgency (71.0%), nocturia (65.7%), and stress incontinence (52.3%) a \u201cfew times\u201d or more in the last 7 days. Approximately half reported sensation of incomplete bladder emptying (49.6%) with one\u2010third reporting urgency incontinence (37.6%); notably, 52.6% of respondents reported being at least \u201csomewhat\u201d bothered by LUTS. LURN\u2010SI\u201029 scores increased with age, body mass index, decrements in self\u2010reported health, medical comorbidity, parity, menopausal status, and urinary symptom bother, providing evidence of convergent validity. LURN\u2010SI\u201029 scores varied by race and education, with the lowest scores in Asian and highly educated women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Overall, the prevalence and spectrum of LUTS in an online research registry of women volunteers were high and comparable to other population\u2010based samples. The new LURN\u2010SI\u201029 demonstrated its ability to detect expected associations with demographic and health characteristics in a nonclinical population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24870","type":"journal-article","created":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T13:44:35Z","timestamp":1642254275000},"page":"650-661","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Survey of lower urinary tract symptoms in United States women using the new lower urinary tract dysfunction research Network\u2010Symptom Index 29 (LURN\u2010SI\u201029) and a national research registry"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9784-2559","authenticated-orcid":false,"given":"Ariana L.","family":"Smith","sequence":"first","affiliation":[{"name":"Division of Urology Perelman School of Medicine at the University of Pennsylvania Philadelphia Philadelphia Pennsylvania 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