{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T23:16:25Z","timestamp":1770678985783,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T00:00:00Z","timestamp":1643068800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012416","name":"Inova Health System","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012416","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate how aging and menopausal status in absence of pregnancy and childbirth affect the elasticity of the bladder and urethra.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>A single\u2010center prospective observational study including nulliparous 10 pre\u2010 and 12 postmenopausal women. Data collection included baseline characteristics, physical examination data, questionnaire scores, PDFI and the Pelvic Floor Impact Questionnaire, and pelvic floor sonographic measurements as well as elastography measurements. The shear wave elastography (SWE) of tissue was measured using Kilopascal (kPa). The elastography measurements were taken over the rhabdosphincter, the suburethra smooth muscle, and the trigonal areas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 22 nulliparous subjects were enrolled in the study. The cohort's mean age was 43.5 years, the mean body mass index (BMI) was 26.8, and 86% were of Caucasian ethnicity. The postmenopausal group was older and with higher BMI (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 and <jats:italic>p<\/jats:italic>\u2009=\u20090.05). They also had higher scores in all the questionnaires (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05 for all) and did not demonstrate prolapse in any compartments. The SWE results for the whole group were 35.2\u2009kPa in the rhabdosphincter measuring point, 40.2\u2009kPa in the sub\u2010urethra point, and 20.6\u2009kPa in the trigone point. Comparing the premenopause and postmenopause groups, we found lower measurements in the rhabdosphincter area and equivocal measurements for the suburethral zone. No statistically significant differences were found between the groups<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The elastic properties of the different bladder components and the urethra change with age and menopause. Using elastic properties of the tissues, we can further explore both stress urinary incontinence and overactive bladder.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24877","type":"journal-article","created":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T20:44:36Z","timestamp":1643143476000},"page":"797-805","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Does aging affect the elastic properties of the bladder and the urethra in nulliparous women: An ultrasound shear\u2010wave elastography study"],"prefix":"10.1002","volume":"41","author":[{"given":"Yael","family":"Baumfeld","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology INOVA Women's Hospital Inova Health System  Falls Church Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Bioengineering George Mason University  Fairfax Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paraq","family":"Chitnis","sequence":"additional","affiliation":[{"name":"Department of Bioengineering George Mason University  Fairfax Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna","family":"Marroquin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology INOVA Women's Hospital Inova Health System  Falls Church Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5513-5955","authenticated-orcid":false,"given":"S. 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