{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T20:27:49Z","timestamp":1776371269873,"version":"3.51.2"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,2,19]],"date-time":"2022-02-19T00:00:00Z","timestamp":1645228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>While behavior\u2010based pelvic floor muscle exercise therapy is an effective treatment for overactive bladder in Parkinson's disease (PD) patients, cognitive function may be a predictor of rehabilitation outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a planned exploratory analysis, participants who had a Montreal Cognitive Assessment (MoCA) with a score \u226518 who were randomized in a clinical trial to behavioral treatment were classified by perceived improvement (<jats:italic>Benefit<\/jats:italic> vs. <jats:italic>No Benefit<\/jats:italic>) as reported on a validated Satisfaction and Benefit Questionnaire. General cognition (MoCA), motor procedural learning (Serial reaction time task), verbal memory (Buschke delayed recall), spatial memory (Nonverbal\/Spatial selective reminding test), and working memory (Wisconsin card sorting task) were compared between the two groups using Wilcoxon rank\u2010sum test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 26 participants randomized to behavioral treatment (70% male, mean age 71\u2009\u00b1\u20096.1 years), 22 participants (85%) reported <jats:italic>Benefit<\/jats:italic> and four reported <jats:italic>No Benefit<\/jats:italic>. General cognition, motor procedural learning, verbal memory, spatial memory, and working memory did not differ between these groups. While the difference between the time to complete the final practiced series and the random series of the Serial Reaction Time Task (SRTT) was statistically similar between the groups, the <jats:italic>Benefit<\/jats:italic> group performed the random sequence more quickly (567.0\u2009\u00b1\u2009136.5\u2009ms) compared to the <jats:italic>No Benefit<\/jats:italic> group (959.4\u2009\u00b1\u2009443.0\u2009ms; <jats:italic>p<\/jats:italic>\u2009=\u20090.03) and trended toward faster performance in the final practiced series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Perceived benefit from behavioral treatment for overactive bladder was not associated with measures of baseline cognition other than faster completion of the SRTT. This is noteworthy because many behavior\u2010based therapy studies exclude participants with mild cognitive impairment. Additional studies may evaluate if domain\u2010specific cognitive function, particularly the assessment of implicit memory, could lead to individualized behavioral therapy recommendations.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24891","type":"journal-article","created":{"date-parts":[[2022,2,19]],"date-time":"2022-02-19T09:07:51Z","timestamp":1645261671000},"page":"841-846","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Exploratory evaluation of baseline cognition as a predictor of perceived benefit in a study of behavioral therapy for urinary incontinence in Parkinson disease"],"prefix":"10.1002","volume":"41","author":[{"given":"Phat L.","family":"Chang","sequence":"first","affiliation":[{"name":"Division of Geriatrics and Gerontology, Department of Medicine Emory University Decatur Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicia C.","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Department of Neurology Emory University Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn L.","family":"Burgio","sequence":"additional","affiliation":[{"name":"Birmingham\/Atlanta VA Geriatric Research, Education, and Clinical Center Birmingham Alabama USA"},{"name":"Birmingham\/Atlanta VA Geriatric Research, Education, and Clinical Center Atlanta Georgia USA"},{"name":"Division of Gerontology, Geriatrics, and Palliative Care, Department of Medicine University of Alabama at Birmingham Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge L.","family":"Juncos","sequence":"additional","affiliation":[{"name":"Department of Neurology Emory University Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"McGwin","sequence":"additional","affiliation":[{"name":"Birmingham\/Atlanta VA Geriatric Research, Education, and Clinical Center Birmingham Alabama USA"},{"name":"Birmingham\/Atlanta VA Geriatric Research, Education, and Clinical Center Atlanta Georgia USA"},{"name":"Department of Epidemiology University of Alabama at Birmingham Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Muirhead","sequence":"additional","affiliation":[{"name":"Birmingham\/Atlanta VA Geriatric Research, Education, and Clinical Center Birmingham Alabama USA"},{"name":"Birmingham\/Atlanta VA Geriatric Research, Education, and Clinical Center Atlanta Georgia USA"},{"name":"Nell Hodgson Woodruff School of Nursing Emory University Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alayne D.","family":"Markland","sequence":"additional","affiliation":[{"name":"Birmingham\/Atlanta VA Geriatric Research, Education, and Clinical Center Birmingham Alabama USA"},{"name":"Birmingham\/Atlanta VA Geriatric Research, 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