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However, adherence rates to behavioral therapies are as low as 32% at 1 year, only 15%\u201040%\u00a0of treated patients remain on oral medications at 1 year due to several factors (e.g., inadequate efficacy, tolerability, and cost), and 5%\u221210% of OAB patients progress to advanced therapies. While some common barriers to therapy adherence are often fixed (e.g., costs, lack of efficacy, time, side effects, treatment fatigue), many are modifiable (e.g., lack of knowledge, poor relationships, negative experiences, poor communication with providers). Patient\u2010centered care may help address some modifiable barriers. Emerging data demonstrate that patient\u2010centered care in the form of treatment navigators improves OAB therapy adherence and progression to advanced therapies in the appropriate patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There are numerous modifiable barriers to OAB therapy adherence. A patient\u2010centered lens is needed to elicit patient goals, establish realistic treatment expectations, and tailor therapy to improve therapy adherence, optimize outcomes, and reduce healthcare expenditures. Further research is needed to develop and study low\u2010cost, scalable solutions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.24936","type":"journal-article","created":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T04:59:53Z","timestamp":1651726793000},"page":"1983-1992","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Barriers and facilitators to overactive bladder therapy adherence"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6224-6207","authenticated-orcid":false,"given":"Ekene A.","family":"Enemchukwu","sequence":"first","affiliation":[{"name":"Department of Urology Stanford University School of Medicine Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslee L.","family":"Subak","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Stanford University School of Medicine Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6567-6744","authenticated-orcid":false,"given":"Alayne","family":"Markland","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gerontology, Geriatrics, and Palliative Care University of Alabama at Birmingham School of Medicine Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-0976-9"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2001.02228.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22295"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","unstructured":"LightnerDJ GomelskyA SouterL VasavadaSP. 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