{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:09:08Z","timestamp":1790982548684,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Refractory bladder neck contracture (BNC) following transurethral prostatectomy is rare and difficult to manage. Success rate of endoscopic treatment decline considerably after repeated treatments. Bladder neck reconstruction are often the last resort to treat refractory BNC failing endoscopic treatments. In general, experience is limited with this type of bladder neck reconstruction, particularly in adult patients. This study aims to determine the success rate, functional and patient\u2010reported outcomes (PRO) of open Y\u2010V plasty in treatment of refractory BNC after transurethral prostatectomy. The study also aims to determine the rate, and potential predictors of persistent storage symptoms after Y\u2010V plasty.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Between January 2016 and February 2021, 18 consecutive patients with refractory BNC who underwent open Y\u2010V plasty were included in this study. All patients presented with voiding dysfunction after two or more failed attempts of endoscopic treatments followed by a 3\u2010month period of outpatient serial dilation program. Clinicopathological data were extracted from medical records including baseline demographics, aetiology of BNC, previous endoscopic treatment, operative time, length of stay, complications, uroflow findings, International Prostate Symptom Score (IPSS) and OAB\u2010V8. Primary outcome was the success of open YV plasty, defined as no need for further instrumentation such as indwelling catheterization, urethral dilatation, urethrotomy, or open surgery. Simple linear regression analysis was performed to determine predictor factors for postoperative OAB\u2010V8. Variables that showed <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.25 were included in the multiple linear regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Most common aetiology of BNC was transurethral resection of prostate gland (<jats:italic>n<\/jats:italic>\u2009=\u200918, 100%). Mean age at surgery age (SD) was 65.5 (7.3) years. Mean follow\u2010up was 14.8 (7) months. Success rate was 100%. Postoperative Qmax improved significantly [pre\u2010OP 6.7 (8.1)\u2009ml\/s vs.\u00a0post\u2010OP was 14.8 (7.3)\u2009ml\/s, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001]. Mean postvoid residual decreased significantly [pre\u2010OP 223.3 (254.3)\u2009ml vs.\u00a0post\u2010OP 45.1 (71.0)\u2009ml, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01)]. Persistent storage symptoms were reported in 61% of patients. BMI and baseline IPSS score are significant predictors for the postoperative OAB V8 change (adjusted <jats:italic>b<\/jats:italic> (95% confidence interval)\u2009=\u20091.037 (0.2\u20131.9), 0.64 (0.28\u20130.99), respectively, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.59).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Y\u2010V plasty reconstruction for refractory BNC represents a feasible and successful option with high success rate and favorable outcomes. While functional and patient\u2010reported outcomes had significantly improved post\u2010operatively, persistent storage symptoms after this procedure still exist. BMI and baseline IPSS score are significant predictors for persistent storage symptoms after bladder neck reconstruction.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24941","type":"journal-article","created":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T12:29:19Z","timestamp":1651148959000},"page":"1082-1090","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Persistent storage symptoms following Y\u2010V plasty reconstruction for the treatment of refractory bladder neck contracture"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4018-5858","authenticated-orcid":false,"given":"Samer","family":"Shamout","sequence":"first","affiliation":[{"name":"Division of Urology, Department of Surgery University of Calgary  Calgary Alberta Canada"},{"name":"Division of Urology, Department of Surgery McGill University  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1955-6992","authenticated-orcid":false,"given":"Henry H. I.","family":"Yao","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery University of Calgary  Calgary Alberta Canada"},{"name":"Department of Urology, Western Health Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9101-113X","authenticated-orcid":false,"given":"Abubakr H.","family":"Mossa","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery McGill University  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6071-6110","authenticated-orcid":false,"given":"Kevin V.","family":"Carlson","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5839-4909","authenticated-orcid":false,"given":"Richard J.","family":"Baverstock","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.06.005"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.10.082"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.06.017"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.12.042"},{"issue":"2","key":"e_1_2_10_6_1","first-page":"85","article-title":"Bladder neck sclerosis after transurethral resection of the prostate. \u201cStudy Group of the Puigvert Foundation\u201d","volume":"18","author":"Herrando C","year":"1994","journal-title":"Actas Urol Esp"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2013.04.012"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000019620"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11701-017-0708-y"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-016-1779-5"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2018.04.017"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.01.074"},{"issue":"2","key":"e_1_2_10_13_1","first-page":"150","article-title":"The retropubic approach to vesical neck obstruction in children","volume":"96","author":"Young B","year":"1953","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2018.05.007"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-194105000-00004"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq433"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)01048-7"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2013.08.018"},{"key":"e_1_2_10_19_1","first-page":"433","article-title":"Bladder neck resection combined with ten point intralesional mitomycin C injection in management of refractory bladder neck contracture in post TURP status: a single\u2010center, 2\u2010year experience","volume":"12","author":"Selvaraj N","year":"2020","journal-title":"Res Rep Urol"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.08.104"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10132884"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-017-2089-2"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.1930120502"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.12.095"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20619"},{"key":"e_1_2_10_26_1","doi-asserted-by":"crossref","unstructured":"ZhuJ HuX DongX LiL.Associatiracture.Neurourol Urodyn.2022.doi:10.1002\/nau.24941","DOI":"10.1002\/nau.24941"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.24941","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/nau.24941","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.24941","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T17:27:37Z","timestamp":1692811657000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.24941"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,28]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1002\/nau.24941"],"URL":"https:\/\/doi.org\/10.1002\/nau.24941","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,28]]},"assertion":[{"value":"2022-01-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}