{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T12:40:28Z","timestamp":1766407228020},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T00:00:00Z","timestamp":1655856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The objective of this analysis was to describe longitudinal adherence with recommended urinary incontinence (UI) evaluation and treatment guidelines over a 2\u2010year period in patients newly diagnosed with stress (SUI) or mixed UI (MUI), and average 2\u2010year cost associated with initial treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective claims analysis using the IBM MarketScan database was conducted. Women diagnosed with SUI\/MUI between July 1, 2014 and June 30, 2016 were identified using the International Classification of Diseases (ICD) 9 and 10 codes for SUI or MUI. Newly diagnosed SUI\/MUI patients who did not have a UI\u2010related diagnosis for at least 1 year before their index date were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>103\u2009813 patients with newly diagnosed SUI or MUI were identified. Of those, 96.15% (99\u2009821\/103\u2009813) received an initial evaluation in accordance with professional guidelines (e.g., patient history, physical examination, urinalysis). Only 6.8% (5086\/74\u2009925) and 7.7% (2229\/28\u2009888) of patients with SUI and MUI, respectively, received a first\u2010line behavioral treatment (e.g., pelvic floor muscle exercises, bladder training), according to guidelines. The 2\u2010year average UI\u2010related medical costs associated with guideline adherence for SUI were $5770.93\u2009\u00b1\u2009$9454.81 and for MUI, $4416.16\u2009\u00b1\u2009$7401.53. Nonadherence was observed in 59.2% (44\u2009382\/74\u2009925) of SUI and 64.1% (18\u2009530\/28\u2009888) of MUI patients. Two\u2010year average UI\u2010related medical costs for the nonadherent group were $8568.00\u2009\u00b1\u2009$11\u2009275.52 for SUI and $6986.66\u2009\u00b1\u2009$10\u2009765.55 for MUI, significantly more than the adherent group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The majority of SUI or MUI patients do not receive a documented behavioral intervention as their first\u2010line treatment, which is a recommendation by professional society guidelines. This was found to affect the cost burden for payers; those that were nonadherent had significantly higher costs 2\u2010year\u00a0postindex.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.24986","type":"journal-article","created":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T14:10:03Z","timestamp":1655907003000},"page":"1489-1497","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Adherence to professional society guidelines among women with stress or mixed urinary incontinence"],"prefix":"10.1002","volume":"41","author":[{"given":"Li\u2010Chen","family":"Pan","sequence":"first","affiliation":[{"name":"Boston Healthcare Associates, Inc. Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manasi","family":"Datar","sequence":"additional","affiliation":[{"name":"Boston Healthcare Associates, Inc. Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica L.","family":"McKinney","sequence":"additional","affiliation":[{"name":"Renovia, Inc. Boston Massachusetts USA"},{"name":"School of Rehabilitation Sciences Andrews University Berrien Springs Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura E.","family":"Keyser","sequence":"additional","affiliation":[{"name":"Renovia, Inc. Boston Massachusetts USA"},{"name":"Department of Physical Therapy and Rehabilitation Science University of California San Francisco San Francisco CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas F.","family":"Goss","sequence":"additional","affiliation":[{"name":"Boston Healthcare Associates, Inc. Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha J.","family":"Pulliam","sequence":"additional","affiliation":[{"name":"Renovia, Inc. Boston Massachusetts USA"},{"name":"Tufts Medical Center Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,6,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0000000000001127"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000057"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-011-0209-x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2018.04.076"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.11124\/JBISRIR-2017-003389"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20798"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.14927"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2020.101842"},{"key":"e_1_2_9_10_1","unstructured":"SmilenS KentonK.ACOG Practice Bulletin. Urinary incontinence in women. 2018. Accessed August 24 2020.https:\/\/www.acog.org\/-\/media\/Practice-Bulletins\/Committee-on-Practice-Bulletins----Gynecology\/pb155.pdf?dmc=1&ts=20180423T2314120185"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.06.061"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.7326\/M13-2410"},{"issue":"6","key":"e_1_2_9_13_1","first-page":"339","article-title":"Urinary incontinence in women: evaluation and management","volume":"100","author":"Hu JS","year":"2019","journal-title":"Am Fam Physician"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-007-0495-5"},{"key":"e_1_2_9_15_1","doi-asserted-by":"crossref","unstructured":"Hay\u2010SmithE HerderscheeR DumoulinC HerbisonG.Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women (Review).Cochrane Database Syst Rev. 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