{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:19:15Z","timestamp":1790090355579,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T00:00:00Z","timestamp":1664496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Low\u2010energy extracorporeal shock wave therapy (LiESWT) is a new potential treatment for intractable interstitial cystitis\/bladder pain syndrome (IC\/BPS), and this paper will evaluate its therapeutic effects on IC\/BPS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This prospective clinical trial enrolled 30 women who have been diagnosed with IC\/PBS to receive LiESWT treatment at an intensity of 0.25\u2009mJ\/mm<jats:sup>2<\/jats:sup> and a frequency of 3 pulses\/second, for a total of 3000 pulses within 8 weeks. And we assessed questionnaires (including O'Leary\u2010Sant Interstitial Cystitis Symptom Index (ICSI)), 3\u2010day voiding diary, and urodynamic study at the following intervals: 4 weeks of LiESWT (W4), 8 weeks of LiESWT (W8), 1\u2010month follow\u2010up (F1), 3\u2010month follow\u2010up (F3) after LiESWT, and 1 year follow\u2010up (F12).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The primary outcome of questionnaires showed significant improvement of symptoms compared to baseline (W0), especially on ICSI(12.87\u2009\u00b1\u20093.44 before treatment and 7.87\u2009\u00b1\u20095.27 at F12, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). 3\u2010day voiding diary also revealed significant decrease in daytime voiding frequency (15.57\u2009\u00b1\u20095.22 times before treatment and 10.70\u2009\u00b1\u20094.21 times at F1, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) and significant increase on average voiding volume (95.85\u2009\u00b1\u200935.30\u2009mL before treatment and 161.27\u2009\u00b1\u200974.21\u2009mL at F1, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). However, there were no significant differences in all parameters of the urodynamic study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LiESWT can mitigate pain and lower urinary tract symptoms and improve the quality of life in IC\/PBS patients, but does not increase the maximal cystometric capacity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.25027","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T07:19:06Z","timestamp":1664522346000},"page":"65-72","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Use of low\u2010intensity extracorporeal shock wave therapy in the management of interstitial cystitis\/bladder pain syndrome patients: A thirty case study in a tertiary medical center"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1100-060X","authenticated-orcid":false,"given":"Lan\u2010Sin","family":"Jhang","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Chang Gung Memorial Hospital, Linkou Medical Center  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu\u2010Chiao","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chang Gung Memorial Hospital, Linkou Medical Center  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4490-8750","authenticated-orcid":false,"given":"Ting\u2010Xuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chang Gung Memorial Hospital, Linkou Medical Center  Taoyuan 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Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Hao","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chang Gung Memorial Hospital, Linkou Medical Center  Taoyuan Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,30]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-020-04232-5"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.09.019"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.03.132"},{"key":"e_1_2_13_5_1","first-page":"331","article-title":"Clinical management of bladder pain syndrome\/interstitial cystitis: a review on current recommendations and emerging treatment options","volume":"12","author":"Colemeadow J","year":"2020","journal-title":"Res Rep 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